Opportunities for the Prevention of Congenital Syphilis in Maricopa County, Arizona

Taylor, Melanie; Mickey, Tom; Browne, Kath; Kenney, Kerry; England, Bob; Blasini-Alcivar, Lily

doi:10.1097/olq.0b013e31815bb335

Cited by 21 publications

(24 citation statements)

References 4 publications

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“…As we demonstrate here, prior studies have consistently found some CS cases related to lack of prenatal care, imperfect screening or treatment, and infections that occur near delivery. 9–11,14,15,29 Eliminating CS requires timely detection and treatment of syphilis in pregnant women, prevention of unintended pregnancies in women at risk of syphilis and, ultimately, the prevention of syphilis among women and their partners. 25,30 …”

Section: Discussionmentioning

confidence: 99%

“…This may be why some mothers with syphilis were not being rescreened in the third trimester, but the data from FL and other studies also demonstrate missed opportunities for third-trimester screening among providers. 11,14,15 …”

Section: Discussionmentioning

confidence: 99%

“…Thus, understanding which populations within an area are at greatest risk for acquiring syphilis can aid in developing and implementing interventions. 11,15,16 …”

Section: Discussionmentioning

confidence: 99%

“…9–11 The benefit of third-trimester screening is highly dependent on the local incidence of syphilis among women. 12,13 Even in areas where third-trimester screening is recommended it has been often been implemented at low rates.…”

mentioning

confidence: 99%

“…9–11 One study among pregnant women with reactive nontreponemal tests (including those who were previously treated) found that earlier access to prenatal care and increasing prenatal visits decreased the odds that the pregnancy would result in a CS case. 16 Another study compared infected pregnant women who did or did not complete treatment, but it did not report on success preventing CS.…”

mentioning

confidence: 99%

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Effectiveness of Prenatal Screening and Treatment to Prevent Congenital Syphilis, Louisiana and Florida, 2013–2014

Matthias¹,

Rahman²,

Newman³

et al. 2017

Sexual Trans Dis

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Background: From 2012 to 2014, rates of congenital syphilis increased in Louisiana and Florida. We evaluated the effectiveness of early (first or second) and third trimester syphilis screening for the prevention of congenital syphilis in these high-morbidity states. Methods: Reported syphilis cases among pregnant women in Louisiana and Florida during January 1, 2013, to December 31, 2014, were reviewed for documented screening for syphilis in the first 2 trimesters and third trimester. Pregnant women with syphilis were linked to congenital syphilis records and stratified by whether the pregnancy led to a reported congenital syphilis case. Results: Seven hundred ten pregnant women with syphilis in Louisiana and Florida were linked to 155 congenital syphilis cases. Three hundred seventy (52%) pregnant women with syphilis were staged as early syphilis (n = 270) or high-titer late or unknown duration-latent syphilis (n = 100), and 109 (70% of the total) were linked to congenital syphilis cases. Screening in the first 2 trimesters identified 513 pregnant women who tested positive for syphilis, and 470 (92%) potential congenital syphilis were averted. One hundred nine pregnant women tested positive for syphilis in the third trimester, and 85 (78%) had babies without congenital syphilis. During their pregnancy, 85 (12%) women tested negative at least once, and 55 (65%) had babies with congenital syphilis. Thirty-nine women had no reported syphilis screening 30 days or longer before delivery. Conclusions: Screening for syphilis both early and in the third trimester prevented many pregnant women with syphilis from having a baby with congenital syphilis. Preventing all congenital syphilis would likely require preventing all syphilis among women.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Thus, understanding which populations within an area are at greatest risk for acquiring syphilis can aid in developing and implementing interventions. 11,15,16 …”

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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