2021
DOI: 10.1111/add.15739
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Opioid overdose deaths and the expansion of opioid agonist treatment: a population‐based prospective cohort study

Abstract: Background and aim: Effective policies to reduce drug-related overdoses remain a public health priority. We aimed to estimate the causal effects of a national opioid agonist treatment (OAT) program on population level drug fatalities.Design: Population-based prospective cohort study exploiting supply driven variation in treatment uptake across cohort-age groups generated by the introduction and scale-up of a national OAT program. A Poisson difference-in-differences model with an intentionto-treat design was us… Show more

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Cited by 9 publications
(10 citation statements)
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“…From Norway we have shown OAT to reduce the overdose burden, with one life saved from overdose death for each 100 person-years in OAT [13]. Enrollment into OAT crucially needs to be scaled-up in the United States, including access to all available OAT medications.…”
Section: Suggested Key Areas Of Prioritiesmentioning
confidence: 99%
“…From Norway we have shown OAT to reduce the overdose burden, with one life saved from overdose death for each 100 person-years in OAT [13]. Enrollment into OAT crucially needs to be scaled-up in the United States, including access to all available OAT medications.…”
Section: Suggested Key Areas Of Prioritiesmentioning
confidence: 99%
“…The decline in the burden of premature mortality incurred by drug-induced causes is in line with previous research, which has documented a gradual reduction in mortality rates in the Norwegian population of persons using opioids 58 and after release from prison. 35 This development is likely attributable to the propagation and increased availability of opioid agonist treatment 59 and, in the prison context, targeted efforts to reduce immediate overdose risk following release. 60…”
Section: Discussionmentioning
confidence: 99%
“…The manufacturing and dissemination of illicit fentanyl, as well as other highly toxic and incredibly harmful synthetic drugs such as P2P methamphetamine, are highly profitable 48. As such, the presence of these drugs and their associated harms will not be eliminated without continued policy change related to how these drugs, those who use these drugs and their treatment are viewed in the USA (ie, legalisation, decriminalisation and medication-assisted treatment) 49–53…”
Section: Discussionmentioning
confidence: 99%