2023
DOI: 10.21203/rs.3.rs-2515135/v1
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Opioid Free Versus Opioid Based Anesthesia in Major Spine Surgery: A Prospective, Randomized, Controlled Clinical Trial

Abstract: Background: The aim of this study is to compare the intraoperative opioid free anesthesia approach to the conventional opioid based anesthesia in patients undergoing multilevel spinal fusion surgery, and its impact on postoperative pain, opioid consumption, and related side effects. Methods: Forty-eight patients undergoing elective major spine surgery were randomly allocated to two groups. The Opioid-Free Anesthesia (OFA) group received dexmedetomidine 0.5mcg/kg/hr and lidocaine 1mg/kg/hr as continuous intrave… Show more

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