Opioid dependency and intervention: A critical examination of the neurobiological foundations
Pallavi Nidode,
Charanya Natarajan,
G. Rajathi
et al.
Abstract:Opioids strongly modulate numerous physiological and psychological functions. They may induce euphoria and analgesia, which cultures have sought for generations when administered abruptly. Chronic opioid usage alters neural circuitry and creates a drug-dependent condition. During drug withdrawal, allostatic alterations caused by drug dependence are evident. Drug use stops a temporary coordinated allostatic re-established of neural circuits, which manifest as physiology and psychological consequences that are t… Show more
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