2022
DOI: 10.1016/j.injury.2022.03.068
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Opioid administration in the prehospital setting for patients sustaining traumatic injuries: An evaluation of national emergency medical services data

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Cited by 3 publications
(13 citation statements)
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“…However, our findings do not provide evidence of an association between prehospital analgesia and likelihood of inpatient delirium. These findings, combined with our prior findings that prehospital opioids effectively reduce pain scores in older trauma patients without increasing incidence of adverse events in the prehospital interval, 11 indicate use of prehospital opioid analgesia in injured older adults has both potential clinical benefits and implications for the course of subsequent care, highlighting the need for future investigation to inform specific guidelines for early pain management in this population.…”
Section: Discussionmentioning
confidence: 52%
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“…However, our findings do not provide evidence of an association between prehospital analgesia and likelihood of inpatient delirium. These findings, combined with our prior findings that prehospital opioids effectively reduce pain scores in older trauma patients without increasing incidence of adverse events in the prehospital interval, 11 indicate use of prehospital opioid analgesia in injured older adults has both potential clinical benefits and implications for the course of subsequent care, highlighting the need for future investigation to inform specific guidelines for early pain management in this population.…”
Section: Discussionmentioning
confidence: 52%
“…However, it is unlikely the relationship between prehospital opioids and clinical outcomes has changed. Our prior work indicated a correlation between pain scores and likelihood of prehospital opioid administration, 11 raising concerns about confounding by indication. We used IPTW to reduce likelihood of bias from confounding by indication.…”
Section: Discussionmentioning
confidence: 94%
“…Providing opioid analgesia must be undertaken with care in the austere environment as opioid use can be associated with a wide range of side effects, most concerningly respiratory depression and loss of airway protective reflexes. Other opioid side effects include dysphoria, euphoria, pruritus, nausea, vomiting, and constipation.. 82,83,84 Nonetheless, opioids have an established role in the treatment of severe acute pain in the wilderness or austere environment. 82,85,86 Choice of opioid, route of administration, and dosage are dependent upon many factors, including scope of practice, mechanism and extent of injuries, logistical issues of extraction and transport of the patient, comorbidities, and presence of hypovolemic shock.…”
Section: Opioid Analgesiamentioning
confidence: 99%
“…With careful titration and administration by experienced physicians and other providers, these problems can usually be avoided. 82,85 Whether opioids are part of the analgesic plan for an expedition, personal use, or wilderness EMS, consideration should be given to management of complications, and a risk/benefit analysis must be performed in advance of carrying and administering opioids. At a minimum, providers administering opioid analgesia should have basic training in airway management as this is the primary means of managing respiratory depression due to opioid use.…”
Section: Opioid Analgesiamentioning
confidence: 99%
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