Abstract:Findings were consistent with CIMT trials and surveys regarding client compliance difficulties and therapist misgivings. Findings argue for continued refinement of modified CIMT regimens as well as greater educational efforts regarding CIMT for therapists.
“…40Y45 There are some concerns that the CIMT approach is a very challenging regimen that requires constraining the normal limb for a long period. 46 Many stroke patients have difficulty performing the task and have poor compliance at home. Hayner et al 47 found that CIMT and bilateral treatment with equal intensity can improve upper limb function without a difference between groups, which indicated that treatment intensity rather than restraint may be the essential therapeutic factor.…”
Exercise training promotes axonal recovery, which is associated with functional improvement after cerebral infarction. Down-regulation of the Nogo-A/NgR1/Rho-A may mediate the axonal remodeling induced by exercise training.
“…40Y45 There are some concerns that the CIMT approach is a very challenging regimen that requires constraining the normal limb for a long period. 46 Many stroke patients have difficulty performing the task and have poor compliance at home. Hayner et al 47 found that CIMT and bilateral treatment with equal intensity can improve upper limb function without a difference between groups, which indicated that treatment intensity rather than restraint may be the essential therapeutic factor.…”
Exercise training promotes axonal recovery, which is associated with functional improvement after cerebral infarction. Down-regulation of the Nogo-A/NgR1/Rho-A may mediate the axonal remodeling induced by exercise training.
“…However, the approach has not been widely applied to routine clinical practice [19]. Evidence suggests that both clinicians and patients express concern about its clinical feasibility and that they poorly understand the intervention protocol [20][21][22][23]. To add to their confusion, even the scientific literature inconsistently describes the approach.…”
Section: Challenge Of Research Translationmentioning
“…During the last 20 years, constraint-induced movement therapy (CIMT) has evolved as a treatment aiming to improve upperlimb function in patients after a stroke (1). The feasibility of the high-intensity treatment has been questioned by patients and therapists (2)(3)(4)(5). Although several meta-analyses (6)(7)(8)(9) have found evidence that CIMT applied during the chronic phase is effective, the effect in the early phase after stroke is uncertain (10), and there is limited information about adherence to the treatment (11,12).…”
Overall adherence was good; however, time spent in motor activity was only one-third of total treatment time. The parameters in the constraint-induced movement therapy protocol should be individually adjusted early after stroke.
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