Opiate Receptors

Abstract

The molecular basis for the observed pharmacological functions of opioid analgesic drugs is defined by multiple opioid receptors.

Sugar Derivatives of Morphine: A New Window for the Development of Potent Anesthetic Drugs

“…There are three major types of opioid receptors: mu (μ), delta (δ) and kappa (κ). Morphine ( 1 ) is an agonist and partial agonist of μ and δ opioid receptors, respectively [ 20 ]. Opioid receptors are mainly localized in the limbic system.…”

“…Opioid receptors are mainly localized in the limbic system. They are involved in the control of emotion and reward behaviors; the ascending and descending pain pathways that include the different laminae layers of cortex, thalamus, periaqueductal grey, midbrain median raphae and the dorsal horn of the spinal cord; and specific brain regions that are known to control locomotion, emesis, cough and temperature [ 20 ]. Some pharmacological effects associated with opioid receptor types are presented in Table 2 .…”