Ophthalmologic Examination of Patients With Seasonal Affective Disorder, Before and After Bright Light Therapy

Gallin, Pamela F.; Terman, Michael; Remé, Charlotte E.; Rafferty, Brian T.; Terman, Jiuan Su; Burde, Ronald M.

doi:10.1016/s0002-9394(14)73874-7

Cited by 119 publications

(57 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Persons using photosensitizing medications should avoid light therapy (94). Opththalmologic evaluations have shown no damage to the eyes of long-term light therapy (95). Still, for subjects with eye diseases, we recommend light therapy only after consultation with an ophthalmologist.…”

Section: General Comments On the Use Of Bright Light Therapymentioning

confidence: 99%

Measures to counteract the negative effects of night work

Pallesen¹,

Bjorvatn²,

Magerøy³

et al. 2009

Scand J Work Environ Health

View full text Add to dashboard Cite

Section: General Comments On the Use Of Bright Light Therapymentioning

confidence: 99%

Measures to counteract the negative effects of night work

Pallesen¹,

Bjorvatn²,

Magerøy³

et al. 2009

Scand J Work Environ Health

View full text Add to dashboard Cite

“…Some preceding studies have reported that no side effects were observed in hospitalized patients treated with higher bright light levels, using artificial lighting devices [2,8,9,15] . However, it may be necessary to consider the possibility for such an intervention approach to light environments as a physical environmental factor to cause stress in perioperative patients who tend to be mentally and physically unstable.…”

Section: Ethical Considerationsmentioning

confidence: 94%

Bright light treatment for prevention of perioperative delirium in elderly patients

Taguchi¹

2013

JNEP

View full text Add to dashboard Cite

Background: Bright light treatment aims to improve circadian rhythms in patients living indoors with poor light-dark transitions by complementing insufficient natural light and highlighting the difference between their day-and night-time activities. In addition to bright light treatment, it is called "phototherapy" or "high-intensity light therapy", and has been reported to be effective to prevent delirium and sleep disorders in the elderly. Under such circumstances, this study examined the validity of bright light treatment as a perioperative care approach for the elderly who are regarded as vulnerable to delirium due to hospitalization or therapeutic intervention. Methods:The study was conducted in the mixed surgical ward of approximately 200 beds, located in Kyoto Prefecture. Subjects were elderly male and female patients who underwent surgery for lower limbs, mainly the femur, and were randomly divided into intervention and control groups. The intervention group received bright light treatment with approximately 2,500 lx of bright light from the day after admission; on the day of surgery and at postoperative week 1, while the control group was treated with normal light during this period. The evaluation of delirium was conducted based on the results of nurses' observation and the Japanese-Version NEECHAM Confusion Scale (NEECHAM scale). In addition to this, information regarding the patients' activities of daily living was also collected. As physiological indices, light-exposure-dependent changes in blood serotonin levels and stress-dependent changes in blood cortisol levels were also evaluated. The period of the study was between 2008 and 2010; data were collected from November to February in each year, when the number of target patients increased.Results: As a result, data regarding 24 patients were obtained within this 2-year period. Excluding those with severe dementia, a total of 16 (intervention: 6; and control: 10) were studied. As a result, delirium occurred in the patients who underwent surgery of the lower limbs, mainly the femur, within the period between the day of surgery and postoperative day 3. The type of delirium was hyperactive in all cases, and its symptoms persisted for 3 to 4 days. Conclusion:The incidence of delirium was generally lower in the intervention than in the control group, suggesting the validity of bright light treatment.

show abstract

“…32 In terms of ocular safety, a study of long-term exposure to light treatment did not reveal ophthalmological problems in participants. 33,34 Overall, light therapy is considered well tolerated and safe, and presents with a convincing risk-to-benefit ratio.…”

Section: Light As a Therapeutic Toolmentioning

confidence: 99%

An insight into light as a chronobiological therapy in affective disorders

Walsh¹,

Atkinson²,

Corlett³

et al. 2014

CPT

View full text Add to dashboard Cite

Abstract:The field of chronobiology has vastly expanded over the past few decades, bringing together research from the fields of circadian rhythms and sleep. The importance of the environmental day-night cycle on our health is becoming increasingly evident as we evolve into a 24-hour society. Reducing or changing sleep times against our natural instincts to rest at night has a detrimental impact on our well-being. The mammalian circadian clock, termed "the suprachiasmatic nucleus", is responsible for synchronizing our behavioral and physiological outputs to the environment. It utilizes light transcoded by specialized retinal photoreceptors as its cue to set internal rhythms to be in phase with the light-dark cycle. Misalignment of these outputs results in symptoms such as altered/disturbed sleep patterns, changes in mood, and physical and mental exhaustion -symptoms shared by many affective clinical disorders. Key links to circadian abnormalities have been found in a number of disorders, such as seasonal affective disorder, nonseasonal depression, and bipolar affective disorder. Furthermore, therapies developed through chronobiological research have been shown to be beneficial in the treatment of these conditions. In this article, we discuss the impact of circadian research on the management of affective disorders, giving evidence of how a misaligned circadian system may be a contributor to the symptoms of depression and how moderating circadian rhythms with light therapy benefits patients.

show abstract

Ophthalmologic Examination of Patients With Seasonal Affective Disorder, Before and After Bright Light Therapy

Cited by 119 publications

References 15 publications

Measures to counteract the negative effects of night work

Measures to counteract the negative effects of night work

Bright light treatment for prevention of perioperative delirium in elderly patients

An insight into light as a chronobiological therapy in affective disorders

Contact Info

Product

Resources

About