Ophthalmologic disorders in adolescents with type 1 diabetes

Abstract

Chronic complications of diabetes, including damage to the eye, are seen in patients with type 2 diabetes often soon after diagnosis. This type of diabetes is often diagnosed after a long period of unrecognized and untreated disease. Type 1 diabetes is one of the most common metabolic diseases diagnosed in children, and is associated with the risk of developing multiple chronic complications. Diabetic eye disease can be associated with abnormalities in various eye structures. It should be remembered that early changes in the organ of vision may not give clear clinical symptoms. Their detection requires the use of modern diagnostic methods, which also allow early detection of changes that threaten damage to the eye. The degree of metabolic control, the presence of dyslipidemia, as well as micro-and macroangiopathy affect the development of chronic complications, including changes in the eye. Damage to small blood vessels leads to changes in retinal perfusion and to macular edema. As a result of these changes, diabetic retinopathy develops. Early diagnosis of the above complications allows prevention of their development.

Sulodeksyd – nowy model leczenia wczesnych stadiów retinopatii cukrzycowej

“…As a result of hyperglycemia, glycocalyx and retinal endothelial cells are damaged by ischemia, oxidative stress, and the release of pro-inflammatory factors. Early symptoms of DR include the loss of autoregulation in retinal cells and retinal arteriovenous dilation that raises hydrostatic pressure in the capillaries, causing tissue edema [5]. Damage to the blood-retinal barrier causes fluid and protein deposits to leak from the capillaries into the retina.…”