Ophthalmic Consequences of Syphilis

Begaj, Tedi; Sobrin, Lucia

doi:10.1097/iio.0000000000000410

Cited by 1 publication

(1 citation statement)

References 85 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, in birdshot chorioretinopathy, hypocyanescent spots on indocyanine green angiography (ICGA) are hypothesized to correspond to choroidal infiltrates initially and can evolve to choroidal atrophy as the disease progresses [2]. Ischemia of the choroid can also be seen in some uveitides [3]. For example, systemic lupus erythematosus can manifest as an occlusive choroidal vasculitis, which can, in turn, lead to vascular attenuation as well as chorioretinal atrophy [4].…”

Section: Introductionmentioning

confidence: 99%

Presence of Choroidal Caverns in Patients with Posterior and Panuveitis

Begaj

Yuan

et al. 2023

Biomedicines

Self Cite

View full text Add to dashboard Cite

Choroidal caverns (CCs) have been described in association with age-related macular degeneration and pachychoroid disease. However, it is unknown if caverns are found in patients with chronic non-infectious uveitis (NIU). Herein, we evaluated patients with NIU who had optical coherence tomography and indocyanine green angiography for CCs. Clinical and demographic characteristics were extracted from the chart review. Univariate and multivariate mixed-effects logistical models were used to assess the association between clinical and demographic factors and the presence of CCs. One hundred thirty-five patients (251 eyes) met the inclusion criteria: 1 eye had anterior uveitis, 5 had intermediate uveitis, 194 had posterior uveitis, and 51 had panuveitis. The prevalence of CCs was 10%. CCs were only observed in patients with posterior and panuveitis, with a prevalence of 10.8% and 7.8%, respectively. Multifocal choroiditis (MFC) was the type of uveitis where CCs were most frequently observed, with 40% of eyes with MFC having CCs. In addition, male sex (p = 0.024) was associated with CCs. There was no significant difference in the degree of intraocular inflammation or mean subfoveal choroidal thickness between CC+ and CC− eyes. This is the first study to describe CCs in uveitis. Overall, these findings suggest that caverns may be a sequela of structural and/or vascular perturbations in the choroid from uveitis.

show abstract

Section: Introductionmentioning

confidence: 99%