Ophthalmic Complications of Dengue

Abstract

A case series suggests that the spectrum of complications in dengue infection is widening.

Uveitis following dengue fever

“…Ocular complications reported by Lim et al 7 were mainly confined to the macula. However, in the study by Chan DP et al 8 Eye one case), suggesting widespread inflammatory processes in the eye. Dengue fever can impair the vision ranging from mild blurring of vision to catastrophic and severe blindness.…”

“…The ocular features peak in acute dengue infection corresponds to the nadir of level of platelets and, thus, a common immune-mediated pathogenesis has been suggested for these manifestations. 8,10,11 Low complement C3 and C4 in dengue patients further suggests immune-mediated mechanism. 11 The possibility of specific autoantibodies production against various tissues of eye has been suggested.…”

“…[6][7][8] Anterior segment manifestation has mostly been reported in the form of subconjunctival hemorrhage, which is related to thrombocytopenia. 9 Anterior uveitis has been rarely described in the acute dengue infection.…”

“…9 Anterior uveitis has been rarely described in the acute dengue infection. 8,10 Ocular manifestations are described mostly during the acute stage of the disease. We, hereby, report six cases of uveitis with history of prior dengue infection.…”

Vasculitis: An Unusual Ocular Manifestation of Dengue Fever

“…However, sequential infections with other serotypes may increase the risk of more serious systemic disease, such as dengue hemorrhagic fever or dengue shock syndrome, which are life-threatening. 3 Lately, few isolated case reports have shown that the ophthalmic complications of dengue fever are not as rare as used to be thought before. [3][4][5][6][7][8][9] Any dengue fever patient with complaints of blurring of vision, floaters, scotomas or metamorphopsia must be thoroughly examined.…”