Ophthalmic complications of COVID-19 vaccination

Pawar, Neelam; Maheshwari, Devendra; Ravindran, Meenakshi; Padmavathy, S.

doi:10.4103/ijo.ijo_2122_21

Cited by 20 publications

(27 citation statements)

References 3 publications

(2 reference statements)

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“…Pawar et al reported on a 28-year-old female who developed sudden vision loss OS three weeks after receiving an unspecified COVID-19 vaccination [113]. Examination and imaging were consistent with left optic neuritis.…”

Section: Optic Neuritismentioning

confidence: 99%

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Ocular Complications Following Vaccination for COVID-19: A One-Year Retrospective

et al. 2022

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Vaccination efforts as a mitigation strategy in the corona virus disease 2019 (COVID-19) pandemic are fully underway. A vital component of understanding the optimal clinical use of these vaccines is a thorough investigation of adverse events following vaccination. To date, some limited reports and reviews have discussed ocular adverse events following COVID-19 vaccination, but a systematic review detailing these reports with manifestations and clinical courses as well as proposed mechanisms has yet to be published. This comprehensive review one-year into vaccination efforts against COVID-19 is meant to furnish sound understanding for ophthalmologists and primary care physicians based on the existing body of clinical data. We discuss manifestations categorized into one of the following: eyelid, orbit, uveitis, retina, vascular, neuro-ophthalmology, ocular motility disorders, and other.

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Section: Optic Neuritismentioning

confidence: 99%

“…Pawar et al reported on a series of three cases of gaze palsies [113]. They reported on a 24-year-old woman who developed diplopia 21 days after unspecified COVID-19 vaccination.…”

Section: Ocular Gaze Palsiesmentioning

confidence: 99%

Ocular Complications Following Vaccination for COVID-19: A One-Year Retrospective

et al. 2022

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“…At present, there are 22 cases with neuro-ophthalmic adverse effects [ Table 4 ]. [ 39 50 51 52 53 54 55 56 57 58 59 ] These aside, Shemer et al .have reported 21 cases of patients with acute facial palsy following COVID-19 vaccination in a retrospective case-control study. [ 60 ] These cases have not been included in the Table 4 as all the details of the individual cases were not available.…”

Section: Neuro-ophthalmic Manifestations Of Covid-19 Vaccinementioning

confidence: 99%

“…The second case of optic neuritis was in a healthy 28-year-old female after the first dose of vector-based Covishield vaccine. [ 53 ] Immune-mediated optic neuritis has been documented with BCG, hepatitis B, and tetanus vaccines.…”

Section: Neuro-ophthalmic Manifestations Of Covid-19 Vaccinementioning

confidence: 99%

“…[ 54 ] Two cases have been reported from India after the vector-based Covishield vaccine. [ 53 ] Abducens nerve palsy has been described following immunization with diphtheria-pertussis-tetanus (DPT), measles-mumps-rubella (MMR), hepatitis B, and influenza vaccine and can occur any time between 2 days and 3 weeks with spontaneous, slow resolution. An immune-mediated vasculitis, thrombosis, or demyelination have been proposed as possible mechanisms for the vaccine-associated nerve palsy.…”

Section: Neuro-ophthalmic Manifestations Of Covid-19 Vaccinementioning

confidence: 99%

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After the Storm: Ophthalmic Manifestations of COVID-19 Vaccines

Sen

Honavar

2021

Indian Journal of Ophthalmology

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Several COVID-19 vaccines have been developed and approved for use around the world from December 2020, to combat the pandemic caused by the novel SARS-CoV-2 virus. Several ophthalmic manifestations of the COVID-19 vaccines have been reported by ophthalmologists. This review was undertaken to recognize, encourage active reporting and determine the pathogenesis and time of appearance for better awareness and understanding of the ophthalmic manifestations of COVID-19 vaccines. A literature search was performed for publications on the ophthalmic manifestations of COVID-19 vaccines between January 1, 2021 and November 7, 2021. 23 case reports, 17 letters to editors, 3 ophthalmic images, 4 brief communications, 4 retrospective cohort studies and 2 case control studies were included. Posterior segment, including the uvea, choroid and retinal vasculature, was most commonly affected and the reported clinical features developed at a median of four days from the time of vaccination. The possible mechanisms include molecular mimicry of the vaccine components with host ocular tissues, antigen-specific cell and antibody-mediated hypersensitivity reactions to viral antigens and adjuvants present in the vaccines. The causal relationship of the ocular signs and symptoms and COVID-19 vaccines has not been established and requires long-term and large multicentre data. Most of the reported manifestations are mild, transient and adequately treated when diagnosed and managed early. The benefits of COVID-19 vaccination outweighs the reported rare adverse events and should not be a deterrent to vaccination.

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