Operative Results after Primary and Secondary Debulking‐Operations in Advanced Ovarian Cancer (AOC)

Lichtenegger, W.; Sehouli, Jalid; Buchmann, E; Karajanev, Constanza; Weidemann, H.

doi:10.1111/j.1447-0756.1998.tb00122.x

Cited by 51 publications

(25 citation statements)

References 8 publications

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“…(15) Para que seja atingida uma citorredução ótima nos casos de doença pélvica extensa que comprometa estruturas adjacentes ao trato genital feminino torna-se necessá-rio na maioria das pacientes uma ressecção do retosigmóide ou mesmo do trato urinário inferior (parcial ou total). A ressecção anterior baixa em monobloco foi (15)(16)(17)(18)(19) Ao utilizar a técnica descrita como exenteração pélvica posterior modificada, Eisenkop et al (5) conseguiram citorredução ótima (sem doença residual macroscópica) na pelve, em 18 de 47 (38,8%) pacientes com câncer de ovário avançado. Após uma mediana de tempo de seguimento de 13,3 meses em 15 (40,5%) das pacientes primariamente operadas não foi observada recorrência pélvica.…”

Section: Discussionunclassified

Os benefícios da ressecção anterior baixa em monobloco para o câncer de ovário avançado: dez anos de experiência em um único centro terciário

Costa

Lupinacci

2008

Rev bras. colo-proctol.

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Trabalho realizado no Serviço de Cirurgia Geral e Oncocirurgia do Hospital do Servidor Público Estadual de São Paulo -"Francisco INTRODUÇÃOAproximadamente 14,300 mulheres faleceram devido ao câncer de ovário em 2003, nos Estados Unidos. Neste país, esta neoplasia representa a principal causa de morte por câncer ginecológico. Em linhas gerais, o câncer de ovário corresponde respectivamente a 4% de todos os diagnósticos de câncer e cerca de 5% de todos os óbitos por câncer. Em estádios precoces é freqüentemente curável. Infelizmente, 60-70 % das pacientes apresentam-se em um estádio avançado no momento de seu diagnóstico. A despeito do fato de que a maioria das pacientes responde (80%) inicialmente a quimioterapia, a maior parte sucumbe em virtude da enfermidade. Os índices de sobrevida global em cinco anos nos estádios avançados têm se situado em torno de 10 %. Quando um tumor de ovário avançado é descoberto durante a avaliação intra-operató-ria, a conduta padronizada é um adequado estadiamento cirúrgico associado a uma citorredução agressiva. A

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Section: Discussionunclassified

Os benefícios da ressecção anterior baixa em monobloco para o câncer de ovário avançado: dez anos de experiência em um único centro terciário

Costa

Lupinacci

2008

Rev bras. colo-proctol.

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“…Wound complications, septicemia, and anastomotic leak formation are more frequent in patients with preoperative serum albumin level of less than 30 g/l [20]. To perform optimal surgery, besides combined bowel resection, procedures such as small-bowel resection, colon resection, nephrectomy, splenectomy, urinary bladder resection, and diaphragm resection have been reported [21,22,23 ]. Radical multivisceral surgery is feasible, safe, and efficient as a primary as well a secondary procedure [22].…”

Section: Surgical Procedures and Morbidity Of Intestinal Surgerymentioning

confidence: 98%

“…To perform optimal surgery, besides combined bowel resection, procedures such as small-bowel resection, colon resection, nephrectomy, splenectomy, urinary bladder resection, and diaphragm resection have been reported [21,22,23 ]. Radical multivisceral surgery is feasible, safe, and efficient as a primary as well a secondary procedure [22]. In terms of technique, the Cavitron Ultrasonic Surgical Aspirator is invaluable to obtain minimal residual disease of small-bowel metastases while avoiding intestinal resection [24].…”

Section: Surgical Procedures and Morbidity Of Intestinal Surgerymentioning

confidence: 99%

Intestinal surgery in advanced ovarian cancer

Takahashi

Tanaka

2007

Current Opinion in Obstetrics &Amp; Gynecology

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By performing aggressive intestinal surgery such as combined bowel resection, optimal cytoreductive surgery can be performed in 70-98% of cases. The morbidity associated with intestinal surgery is acceptably low. Prognostic benefits for intestinal surgery are clear in patients with operable ovarian cancer with no residual disease. Women with suspected ovarian cancer should therefore be referred to centers with experienced tumor surgeons.

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“…According to the FIGO classification, the state-of-the-art surgical treatment includes a detailed exploration of the entire abdomen, bilateral salpingo-oophorectomy (BSO), hysterectomy, omentectomy, peritoneal lavage (or ascites sample) and peritoneal biopsies and resection of all suspected lesions (Trope et al, 2000;Schmalfeldt and Pfisterer, 2007). For mucinous tumours, an appendectomy should be performed to exclude any ovarian metastasis of possible mucinous tumour of the appendix (Lichtenegger et al, 1998;Cadron et al, 2007;Schmalfeldt and Pfisterer, 2007).…”

Section: Surgical Therapymentioning

confidence: 99%

Clinical management of borderline tumours of the ovary: results of a multicentre survey of 323 clinics in Germany

Coumbos¹,

Sehouli

Chekerov

et al. 2009

Br J Cancer

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The aim of this survey was to analyse the standard of care in diagnostic, surgery, chemotherapy and aftercare management for patients with borderline tumours of the ovary (BOTs) in Germany. A structured questionnaire comprising different dimensions was sent to all 1114 gynaecological departments. The questionnaire could be returned anonymously. The overall response rate was 29.0% (323 departments). Most departments were on secondary care (71.8%), tertiary care (23.2%) or university hospital (5.0%) level. Most clinicians performed not more than five BOT operations (89.2%) per year. Most departments (93.2%) used in addition to classical bimanual examination and vaginal ultrasound, tumour marker CA-125 detection, CT scan, MRI or PET-CT techniques. Departments in university and tertiary care hospitals performed more often a fresh frozen section (87 vs 64%). In young women, clinicians performed much seldom unilateral salpingo-oophorectomy (92%) and only in 53% biopsies of the contralateral ovary. Generally, biopsies of the contralateral ovary were performed in 4 -53% of the patients. Chemotherapy was mostly favoured in 'high-risk' patients with tumour residual, microinvasion or invasive implants. Thus, a high grade of insecurity in diagnostic and therapy of BOT exists in some gynaecological departments and underlines the need for more educational and study activities.

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Operative Results after Primary and Secondary Debulking‐Operations in Advanced Ovarian Cancer (AOC)

Abstract: Radical multivisceral surgery is feasible, safe and efficient in primary as well in secondary situation of advanced ovarian cancer.

Cited by 51 publications

References 8 publications

Os benefícios da ressecção anterior baixa em monobloco para o câncer de ovário avançado: dez anos de experiência em um único centro terciário

Os benefícios da ressecção anterior baixa em monobloco para o câncer de ovário avançado: dez anos de experiência em um único centro terciário

Intestinal surgery in advanced ovarian cancer

Clinical management of borderline tumours of the ovary: results of a multicentre survey of 323 clinics in Germany

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