OpenMandible: An open-source framework for highly realistic numerical modelling of lower mandible physiology

Vukićević, Arso M.; Zelić, Ksenija; Milašinović, Danko; Sarrami‐Foroushani, Ali; Jovičić, Gordana; Milovanović, Petar; Djurić, Marija; Filipović, Nenad; Frangi, Alejandro F.

doi:10.1016/j.dental.2021.01.009

Cited by 9 publications

(9 citation statements)

References 59 publications

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“…The bone (cortical and trabecular) contains a microstructure that is the source of anisotropy in mechanical properties and significantly alters elastic response and hence the stiffness as well 39 – 41 . The direction of anisotropy is known for long bones and for mandible 42 , 43 . Nevertheles, little is known for the pelvic bone.…”

Section: Discussionmentioning

confidence: 99%

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Mechanical metric for skeletal biomechanics derived from spectral analysis of stiffness matrix

Henyš

Kuchař

Hájek

et al. 2021

Sci Rep

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A new metric for the quantitative and qualitative evaluation of bone stiffness is introduced. It is based on the spectral decomposition of stiffness matrix computed with finite element method. The here proposed metric is defined as an amplitude rescaled eigenvalues of stiffness matrix. The metric contains unique information on the principal stiffness of bone and reflects both bone shape and material properties. The metric was compared with anthropometrical measures and was tested for sex sensitivity on pelvis bone. Further, the smallest stiffness of pelvis was computed under a certain loading condition and analyzed with respect to sex and direction. The metric complements anthropometrical measures and provides a unique information about the smallest bone stiffness independent from the loading configuration and can be easily computed by state-of-the-art subject specified finite element algorithms.

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Section: Discussionmentioning

confidence: 99%

“…Nevertheles, little is known for the pelvic bone. The artifitial direction 43 or X-ray based direction field 40 , 44 was considered for mandible bone with good accuracy in mechanical response. These approachech could be the good initial attemp for pelvic bone.…”

Section: Discussionmentioning

confidence: 99%

Mechanical metric for skeletal biomechanics derived from spectral analysis of stiffness matrix

Henyš

Kuchař

Hájek

et al. 2021

Sci Rep

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“…The bone (cortical and trabecular) contains a microstructure that is the source of anisotropy in mechanical properties and significantly alters elastic response and hence the stiffness as well [39][40][41] . The direction of anisotropy is known for long bones and for mandible 42,43 . Nevertheles, little is known for the pelvic bone.…”

Section: Study Limitationsmentioning

confidence: 99%

Mechanical Metric for Skeletal Biomechanics Derived from Spectral Analysis of Stiffness matrix

Henyš

Kuchař

Hájek

et al. 2021

Preprint

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“…More specifically, in the orthodontic and dental fields of studies, FEM is utilized to predict teeth movements, stress/strain distribution in different tissues (e.g., periodontal ligament, gingiva, and alveolar bone) or orthodontic appliances [3]. Except for a few recent studies [4,5,6], almost all of the previous studies in the field are limited to single-patient analysis [7,8,9,2,10,11], in which the results might not be generalized to a larger population with high geometrical variations in the teeth, periodontal ligament (PDL), and bone anatomies [4,6].…”

Section: Introductionmentioning

confidence: 99%

“…The main reason for using a single model in the literature is that developing accurate computational models of the human jaw is challenging and involves timeconsuming and labor-intensive processes such as segmentation, geometry reconstruction, geometry processing, remeshing, and mesh simplification tasks. For instance, generating a complex and highly detailed finite element (FE) model of the entire human jaw can take up to several months per scan [10]. Therefore, developing several patient-specific FE models may not be feasible for many researchers.…”

Section: Introductionmentioning

confidence: 99%

Open-Full-Jaw: An open-access dataset and pipeline for finite element models of human jaw

Gholamalizadeh,

Moshfeghifar,

Ferguson

et al. 2022

Preprint

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Background. State-of-the-art finite element studies on human jaws are mostly limited to the geometry of a single patient. In general, developing accurate patient-specific computational models of the human jaw acquired from cone-beam computed tomography (CBCT) scans is labor-intensive and non-trivial, which involves time-consuming human-in-theloop procedures, such as segmentation, geometry reconstruction, and re-meshing tasks. Therefore, with the current practice, researchers need to spend considerable time and effort to produce finite element models (FEMs) to get to the point where they can use the models to answer clinically-interesting questions. Besides, any manual task involved in the process makes it difficult for the researchers to reproduce identical models generated in the literature. Hence, a quantitative comparison is not attainable due to the lack of surface/volumetric meshes and FEMs. Methods.We share an open-access repository composed of 17 patient-specific computational models of human jaws and the utilized pipeline for generating them for reproducibility of our work. The used pipeline minimizes the required time for processing and any potential biases in the model generation process caused by human intervention. It gets the segmented geometries with irregular and dense surface meshes and provides reduced, adaptive, watertight, and conformal surface/volumetric meshes, which can directly be used in finite element (FE) analysis.Results. We have quantified the variability of our 17 models and assessed the accuracy of the developed models from three different aspects; (1) the maximum deviations from the input meshes using the Hausdorff distance as an error measurement, (2) the quality of the developed volumetric meshes, and (3) the stability of the FE models under two different scenarios of tipping and biting.Conclusions. The obtained results indicate that the developed computational models are precise, and they consist of quality meshes suitable for various FE scenarios. We believe the provided dataset of models including a high geometrical variation obtained from 17 different models will pave the way for population studies focusing on the biomechanical behavior of human jaws.

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OpenMandible: An open-source framework for highly realistic numerical modelling of lower mandible physiology

Cited by 9 publications

References 59 publications

Mechanical metric for skeletal biomechanics derived from spectral analysis of stiffness matrix

Mechanical metric for skeletal biomechanics derived from spectral analysis of stiffness matrix

Mechanical Metric for Skeletal Biomechanics Derived from Spectral Analysis of Stiffness matrix

Open-Full-Jaw: An open-access dataset and pipeline for finite element models of human jaw

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