Abstract:Skin mottling and an increased delta temperature (deltaT) between core and peripheral sides as measurements of microcirculatory dysfunction are associated with increased mortality in intensive care patients. We studied the effect on deltaT of ketanserin, a 5-HT2 receptor-blocking agent.
MethodsA retrospective analysis was performed of all intensive care patients that received ketanserin by continuous infusion. Over four to eight consecutive hours the change in deltaT (forefoot) was determined. To exclude lead-… Show more
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