Open-source lab hardware: Driver and temperature controller for high compliance voltage, fiber-coupled butterfly lasers

Kehl, Florian; Cretu, Vlad; Willis, Peter

doi:10.1016/j.ohx.2021.e00240

Cited by 5 publications

(2 citation statements)

References 9 publications

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“…Controlled pneumatic pressure (0–15 psi) applied to the anode reservoir allowed for capillary conditioning and hydrodynamic injection of the sample plug. The custom epifluorescent LIF detector used a 488 nm laser (QFLD-488–20S, QPhotonics, MI, USA) for the excitation of the fluorescent label and a photomultiplier tube (PMT) (H10721–210, Hamamatsu, Japan) for the emission signal detection. , The LIF signal, separation voltage, and the current were recorded at 8 Hz, and the flow and temperature inside the capillary at 2.5 Hz. In accordance with the datasheet, the response time to flow changes is 40 ms.…”

Section: Methodsmentioning

confidence: 99%

Providing Enhanced Migration Time Reproducibility with a High-Voltage-Compatible Flow Sensor for Capillary Electrophoresis

et al. 2022

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In capillary electrophoresis (CE), analyte identification is primarily based on migration time, which is a function of the analyte's electrophoretic mobility and the electro-osmotic flow (EOF). The migration time can be impacted by the presence of parasitic flow from changes in temperature or pressure during the run. Presented here is a high-voltage-compatible flow sensor capable of monitoring the volumetric flow inside the capillary during a separation with nL/min resolution. The direct measurement of both flow and time allows for compensation of flow instabilities. By expressing the electropherogram in terms of signal versus electromigration velocity instead of time, it is possible to improve the run-to-run reproducibility up to 25×.

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Section: Methodsmentioning

confidence: 99%

Providing Enhanced Migration Time Reproducibility with a High-Voltage-Compatible Flow Sensor for Capillary Electrophoresis

et al. 2022

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“…Integrated circuits (ICs) and modules for the applications are also widely available on the market, such as AMC7820, WTC3243, MAX8521, LTC1923 and so on. In addition, compact, low-cost laser temperature controllers are developed in the laboratory, achieving a stability of ±0.01 • C [26,27]. However, higher temperature stability is usually needed in some conditions such as, for example, when the laser wavelength is highly sensitive to temperature.…”

Section: Introductionmentioning

confidence: 99%

Ultra-Stable Temperature Controller-Based Laser Wavelength Locking for Improvement in WMS Methane Detection

Wang

Liang

et al. 2023

Sensors

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In the wavelength modulation spectroscopy (WMS) gas detection system, the laser diode is usually stabilized at a constant temperature and driven by current injection. So, a high-precision temperature controller is indispensable in every WMS system. To eliminate wavelength drift influence and improve detection sensitivity and response speed, laser wavelength sometimes needs to be locked at the gas absorption center. In this study, we develop a temperature controller to an ultra-high stability level of 0.0005 °C, based on which a new laser wavelength locking strategy is proposed to successfully lock the laser wavelength at a CH4 absorption center of 1653.72 nm with a fluctuation of fewer than 19.7 MHz. For 500 ppm CH4 sample detection, the 1σ SNR is increased from 71.2 dB to 80.5 dB and the peak-to-peak uncertainty is improved from 1.95 ppm down to 0.17 ppm with the help of a locked laser wavelength. In addition, the wavelength-locked WMS also has the absolute advantage of fast response over a conventional wavelength-scanned WMS system.

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Open-source lab hardware: A versatile microfluidic control and sensor platform

Kehl¹,

Cretu²,

Willis³

2021

HardwareX

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Here we describe a completely integrated and customizable microfluidic control and sensing architecture that can be readily implemented for laboratory or portable chemical or biological control and sensing applications. The compact platform enables control of 32 solenoid valves, a multitude of pumps and motors, a thermo-electric controller, a pressure controller, and a high voltage power supply. It also features two temperature probe interfaces, one relative humidity and ambient temperature sensor, two pressure sensors, and interfaces to an electrical conductivity sensor, flow sensor, and a bubble detector. The platform can be controlled via an onboard microcontroller and requires no proprietary software.

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Open-source lab hardware: Driver and temperature controller for high compliance voltage, fiber-coupled butterfly lasers

Cited by 5 publications

References 9 publications

Providing Enhanced Migration Time Reproducibility with a High-Voltage-Compatible Flow Sensor for Capillary Electrophoresis

Providing Enhanced Migration Time Reproducibility with a High-Voltage-Compatible Flow Sensor for Capillary Electrophoresis

Ultra-Stable Temperature Controller-Based Laser Wavelength Locking for Improvement in WMS Methane Detection

Open-source lab hardware: A versatile microfluidic control and sensor platform

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