Open Rhinoplasty Using Concealing Incisions for Mild Bifid Nose With Unilateral Mini-Microform Cleft Lip

Mireguli, Tuersunjiang; Long, Xing; Fu, Yuchuan; Ke, Jin; He, Huijun; Li, Jian

doi:10.1097/scs.0000000000004497

Cited by 6 publications

(4 citation statements)

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“… 42 Nevertheless, such microforms may be connected to asymmetry and functional problems of the nostrils and the nose. 34 43 The definitions of the term microform still are not exactly and consistently given in different studies of the last 30 years. Most recent studies, but not all studies, only use the term in connection with cleft lip.…”

Section: Discussionmentioning

confidence: 99%

History of Eugenics in Otorhinolaryngology: Ernst Rüdin and the International Eugenics Network

Suwa

2024

Int Arch Otorhinolaryngol

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Introduction The early geneticist and psychiatrist Ernst Rüdin (1874–1952) became one of the key figures in the eugenics movement and in the German health system of the Nazi era. His connections in the international eugenics network have played an important role in the history of eugenics. Objective To discuss the connections between Ernst Rüdin's scientific group in Munich and Otmar von Verschuer's group in Frankfurt during the Nazi era. Methods Otorhinolaryngological materials from Ernst Rüdin's former private library are presented, and they show Rüdin's deep involvement in the international eugenics network. These materials provide insights into early medical genetics in otorhinolaryngology. Results One result of the present study is that eugenics groups from Munich, Frankfurt, and New York certainly influenced one another in the field of otorhinolaryngology. Karlheinz Idelberger and Josef Mengele were two scientists who performed hereditary research on orofacial clefts. Later, Mengele became deeply involved in Nazi medical crimes. His former work on orofacial clefts clearly had, to some extent, an influence on subsequent studies. Conclusion An international eugenics network already existed before 1933. However, it becomes clear that the weaknesses of many early genetic studies did not enable its authors to draw firm scientific conclusions, suggesting that scientists lacked an accurate concept of the genetic causes of most illnesses.

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Section: Discussionmentioning

confidence: 99%

History of Eugenics in Otorhinolaryngology: Ernst Rüdin and the International Eugenics Network

Suwa

2024

Int Arch Otorhinolaryngol

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“…It increased the scar and secondary operation was usually needed [ 1 ]. Tuersunjiang et al made an inverted-V transcolumellar incision, modified the shape of nose and achieved good results [ 36 ]. Rib cartilage has inherent structural advantage.…”

Section: Discussionmentioning

confidence: 99%

Two novel mutations within FREM1 gene in patients with bifid nose

Chen,

Yu,

Wang

et al. 2023

BMC Pediatr

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Background Bifid nose is a rare congenital deformity and the etiology is unknown. The purpose of this study was to report genetic variation in family of patients with bifid nose. Methods Twenty-three consecutive patients who were diagnosed with mild bifid nose were operated with z-plasty from 2009 to 2021. Three underage patients (a pair of twins and a girl) from two family lines, who came to our hospital for surgical treatment, were enrolled. Whole exome sequencing and Sanger sequencing were conducted. Z-shaped flaps were created and the cartilago alaris major were re-stitched. Photographs and CT scan before and after surgery were obtained. Clinical outcomes, complications and patients’ satisfaction were evaluated and analyzed. The follow-up time ranges from 2 to 3 years (2.4 ± 1.2 years). Results Most patients were satisfied with the outcome (96.2%). The nasal deformities were corrected successfully with z-plasty technique in one-stage. FREM1 c.870_876del and c.2 T > C were detected with Whole exome sequencing, which have not been reported before. The results of Sanger sequencing were consistent with those of Whole exome sequencing. Conclusions The newly detected mutations of FREM1 have a certain heritability, and are helpful to make an accurate diagnosis and provide a better understanding of bifid nose mechanism. Z-plasty technique can be an effective technical approach for correcting mild bifid nose deformity.

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“…Moreover, Tawfik et al adopted the Millard forked flap combined with external rhinoplasty in six cases and obtained good results ( 26 ). Tuersunjiang et al also reported a case performing open rhinoplasty with an inverted-V transcolumellar incision at the middle of the columella and a Tajima incision in mild patients ( 27 ). However, there is still no standard surgical technique.…”

Section: Discussionmentioning

confidence: 99%

“…Remarkably, the Z-shaped flap was the most widely used, which can be used to repair the local deformities of the nasal alar and tip to improve the shape of the alar and its size nostrils. For the selection of scaffold materials, nasal septum or auricular cartilage has been reported ( 25 , 27 ). However, they have a small amount of tissue and are easy to absorb.…”

Section: Discussionmentioning

confidence: 99%

Morphological Analysis of Nose in Patients of Tessier No. 0 Cleft With a Bifid Nose in China

Wang

You

et al. 2021

Front. Pediatr.

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Objective: Facial cleft involves complex malformations. No study assessed the facial deformity of Tessier No. 0 cleft with a bifid nose. Thus, we used anthropometric measurements to access the nose in patients.Methods: A total of 24 bifid nose deformities underwent surgery at our institution between 2010 and 2019. Standardized photographs were taken preoperatively and postoperatively. Landmarks were identified on these images; measurements for nasal analysis were performed and compared with the established Chinese norms. Surgical method differences were also analyzed.Results: The median follow-up time was 2.51 years. Postoperatively, there is a significant difference in comparison with preoperative in the nasal index, medial canthus and nose width index, nasolabial angle, nasofacial angle, ala length and nasal bridge length index, nasal tip protrusion and nasal width index, and nasal width and ala length index. Furthermore, the medial canthus and nose width index, and nasal width and ala length index were significantly larger in ordinary people, while ala length and nasal bridge length index and nasal tip protrusion and nasal width index were smaller. After surgery, most angles and index were standard except the nasolabial angle in the females, and ala length and nasal bridge length index in the males. Moreover, as for the group of costal cartilage transplantation, most index and angles have improved after surgery including nasolabial angle, nasofacial angle, ala length and nasal bridge length index, nasal tip protrusion and nasal width index, and nasal width and ala length index. However, only nasal tip protrusion and nasal width index, columella length and nasal tip protrusion index, and nasal width and ala length index in the silicone prosthesis group implantation has significance. Costal cartilage transplantation can also better improve ala length and nasal bridge length index than the silicone prosthesis implantation.Conclusion: Most defects can be repaired with surgery, but the outcome has a lack of evaluation. Thus, anthropometric assessment can serve as a material for nasal and reconstructive surgery.

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Open Rhinoplasty Using Concealing Incisions for Mild Bifid Nose With Unilateral Mini-Microform Cleft Lip

Cited by 6 publications

References 8 publications

History of Eugenics in Otorhinolaryngology: Ernst Rüdin and the International Eugenics Network

History of Eugenics in Otorhinolaryngology: Ernst Rüdin and the International Eugenics Network

Two novel mutations within FREM1 gene in patients with bifid nose

Morphological Analysis of Nose in Patients of Tessier No. 0 Cleft With a Bifid Nose in China

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