Open radical cystectomy is a reliable surgery with acceptable complication rates in elderly male patients: a retrospective, tertiary hospital-based study

Abstract

Objective: This study aims to evaluate safety of radical cystectomy (RS)þpelvic lymph node dissection (PLND)þileal conduit urinary diversion (ICUD) in male patients aged >65 years versus 65 years. Materials and Methods: Eighty-five male patients who underwent RS þ PLND þ ICUD for bladder cancer were retrospectively analyzed. The patients were divided into two groups according to age: 65 years (Group 1, n ¼ 40) versus >65 years (Group 2, n ¼ 45). Data including baseline demographic and clinical characteristics of the patients, length of hospital stay, and complications within 90 days of surgery, and Grade II and Grade ! III complications according to the Clavien-Dindo (C-D) classification were recorded. Groups were compared in terms of demographic features and development of complications within 90 day after surgery statistically. Results: The median length of hospital stay was statistically significantly longer in Group 2 than Group 1 [10 (7-17) days vs. 9 (6-14) days, respectively; p < .05]. There was no statistically significant difference in the rehospitalization rate within 90 days of surgery between the groups (p > .05). Conclusion:Our study results suggest that RS þ PLND þ ICUD is a safe procedure in male patients aged !65 years.

Testosterone status is not associated with bladder cancer parameters in adult male patients: results of a prospective controlled study

“…The most bothering problem in BCa is that it recurs very often and progresses to the muscle-invasive state [16]. Although there are different local agents used to stop progression, unfortunately they are not really effective in the majority of cases [17]. In terms of relapse, BCa is the cancer type with the highest cost per patient during the period from diagnosis to death because it requires at least follow-up throughout life [18,19].…”

Clinical outcome and quality of life in octogenarian patients with muscle-invasive urothelial carcinoma of the bladder treated with radical cystectomy or transurethral resection of the bladder tumor: a retrospective analysis of 143 patients

“…We think there are several potential reasons for similar results in Clavien–Dindo grade complications in the TURBT and the RC group in the present study. 54.9% of grade 2/3 complications in the RC group is in line with the results of other published RC cohorts in the literature reporting complications between 39 and 68% [ 29 – 31 ]. On the other hand, grade 2/3 complications for TURBT of 65.2% is seemingly higher compared to other studies reporting complication rates between 8.1 and 19.1% [ 32 , 33 ].…”