1968
DOI: 10.1016/0002-9378(68)90401-8
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Open heart surgery during pregnancy

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1971
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Cited by 22 publications
(9 citation statements)
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“…When the patient has sub-acute bacterial endocarditis the maternal mortality is higher if termination is performed than when the pregnancy is allowed to continue (Cates and Christie, 195 1; Barnes, 1968). Nevertheless both medical treatment and heart surgery may carry the risk of producing congenital abnormalities (Meffert and Stansel, 1968).…”
Section: Treatmentmentioning
confidence: 99%
“…When the patient has sub-acute bacterial endocarditis the maternal mortality is higher if termination is performed than when the pregnancy is allowed to continue (Cates and Christie, 195 1; Barnes, 1968). Nevertheless both medical treatment and heart surgery may carry the risk of producing congenital abnormalities (Meffert and Stansel, 1968).…”
Section: Treatmentmentioning
confidence: 99%
“…Additionally, cardiovascular operation using deep hypothermia with total circulatory arrest for aortic repair may be associated with a higher risk of foetal mortality [ 15 ]. Some CPB parameters are adjusted to improve foetal outcome: for example, high flow rates and a target MAP > 70 mmHg are recommended for placental perfusion [ 16 ]. Three pregnant women in the first two trimesters underwent repair first, and successfully gave birth to healthy infants.…”
Section: Discussionmentioning
confidence: 99%
“…The effect of maternal heart-lung bypass on the fetus is not well understood. Fetal hypoxia may occur with diminished placental perfusion which could be caused by lack of pulsatile flow, opening of uterine arterio-venous shunts, uterine arterial spasm during bypass or the possibility that particulate or bubble emboli may interfere with placental circulation during perfusion (Meffert and Stansel, 1968).…”
Section: Discussionmentioning
confidence: 99%
“…REPORTS of the use of open heart surgery during pregnancy have appeared in the literature from time to time (Szekely and Snaith, 1974), but only rarely has fetal monitoring during cardiopulmonary bypass been reported (Koh et al, 1975; Werch and Lambert, 1977). It has been suggested that the fetal mortality can be as high as 33 per cent during open heart surgery (Zitnik et al, 1969) but can be significantly reduced by the routine use of fetal monitoring (Koh et al, 1975).…”
mentioning
confidence: 99%