Open-angle glaucoma in an urban population in southern india

Dandona, Lalit; Dandona, Rakhi; Marmamula, Srinivas; Mandal, Partha Pratim; John, Rajesh K; McCarty, Catherine A.; Rao, Gullapalli N

doi:10.1016/s0161-6420(00)00275-x

Cited by 212 publications

(68 citation statements)

References 17 publications

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“…3 Primary open angle glaucoma (POAG) and pseudo-exfoliation glaucoma (PXFG) are leading causes of blindness in South India. 4,5 Recent evidence suggests a pathogenetic association between POAG and endothelin dependent vascular dysregulation and impaired ocular blood flow. [6][7][8] The concept of immune system facilitating the development of glaucomatous optic neuropathy in some susceptible individuals has gained more credence with evidence accumulating for the causative role of autoantibodies in a number of peripheral neuropathies, for example, Guillain-Barre syndrome.…”

mentioning

confidence: 99%

Helicobacter pylori IgG Antibodies in Aqueous Humor and Serum of Subjects With Primary Open Angle and Pseudo-exfoliation Glaucoma in a South Indian Population

Deshpande

Lalitha

Das

et al. 2008

Journal of Glaucoma

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confidence: 99%

Helicobacter pylori IgG Antibodies in Aqueous Humor and Serum of Subjects With Primary Open Angle and Pseudo-exfoliation Glaucoma in a South Indian Population

Deshpande

Lalitha

Das

et al. 2008

Journal of Glaucoma

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“…Among the risk factors reported increasing age was a consistent risk factor for POAG across all studies 9,13,14,16 . In the Baltimore eye survey 17 , the prevalence of glaucoma among whites was 3.5 times higher for individuals in their 70s than for those in their 30s.Among blacks the ratio was 7.4.Further Ocular Hypertension Treatment Study 18 confirmed on this.…”

Section: Agementioning

confidence: 85%

Relation between Primary Open Angle Glaucoma and Neurodegenerative Diseases-A Case Control Study

M.¹

2017

jmscr

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“…The diagnosis criteria for glaucoma were the following [4, 5]. (1) Primary open-angle glaucoma: (1) IOP measured repeatedly >21 mm Hg; (2) mean defect (MD) ≥3 dB for standard automated perimetry check, or repeatable characteristic visual field defects for glaucoma (such as paracentral scotoma, nasal step, arcuate scotoma), which is in accordance with changes of optic disc but does not include nonspecific changes such as physiological enlargement of blind spot; (3) specific changes under ophthalmofundoscope such as damages to the optic disc, and focal and diffusive RNFL defects, and (4) wide angle of anterior chamber.…”

Section: Objects and Methodsmentioning

confidence: 99%

Retinal Nerve Fiber Layer Images Captured by GDx-VCC in Early Diagnosis of Glaucoma

Wang

Cui²,

Chen³

et al. 2007

Ophthalmologica

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Objectives: To compare differences in retinal nerve fiber layer (RNFL) parameters between normal subjects and patients with various degrees of glaucoma, evaluate the sensitivity and specificity of GDx-VCC parameters, and determine the capability of GDx-VCC parameters and the most valuable indicators for the diagnosis of early glaucoma. Methods: GDx-VCC was used to measure RNFL in 80 patients with early glaucoma (130 eyes), 70 patients with advanced glaucoma (90 eyes) and 40 normal controls (80 eyes). All glaucoma patients were divided into an early glaucoma group and an advanced glaucoma group, according to the mean defect of the visual field. RNFL parameters were compared between normal subjects and patients with various degrees of glaucoma. Receiver operating characteristic (ROC) curves of GDx parameters were drawn to determine the most valuable GDx parameters for the diagnosis of early glaucoma. Results: The RNFLs were significantly thinner in patients with early glaucoma than those in normal subjects; they were also significantly thinner in patients with advanced glaucoma than those in patients with early glaucoma. The differences in all parameters reached statistical significance (p < 0.001). The mean defect of the visual field was significantly correlated with all RNFL parameters (p < 0.001). The areas under the ROC curves were >0.7 for all parameters, which could effectively differentiate early glaucoma from normal subjects. The areas under the ROC curves were 0.81 for nerve fiber indicator and inferior average with better differentiation capability. Conclusions: GDx-VCC can provide quantitative measurements of RNFL thickness for clinical use, which can effectively differentiate patients with early glaucoma from normal subjects, and will be clinically very helpful for the early diagnosis of glaucoma. Nerve fiber indicator and inferior average are the most effective indicators for the early diagnosis of glaucoma.

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Open-angle glaucoma in an urban population in southern india

Cited by 212 publications

References 17 publications

Helicobacter pylori IgG Antibodies in Aqueous Humor and Serum of Subjects With Primary Open Angle and Pseudo-exfoliation Glaucoma in a South Indian Population

Helicobacter pylori IgG Antibodies in Aqueous Humor and Serum of Subjects With Primary Open Angle and Pseudo-exfoliation Glaucoma in a South Indian Population

Relation between Primary Open Angle Glaucoma and Neurodegenerative Diseases-A Case Control Study

Retinal Nerve Fiber Layer Images Captured by GDx-VCC in Early Diagnosis of Glaucoma

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