In 100 consecutive patients with an abnormal cholecystogram a study was carried out to compare the value of the 4‐day Telepaque test, intravenous cholangiography, and operative cholangiography. Of the 100 patients, 87 were shown at operation to have stones in the gall‐bladder and 22 to have stones in the common bile‐duct. In 4 of the latter patients, stones were absent from the gall‐bladder.
Operative cholangiography was the most accurate investigation in the diagnosis of a stone in the common duct; the operative cholangiogram gave definite evidence of stones in the duct in 20 of the patients, and was abnormal in some respect in all of the patients with a stone in the common duct. It is concluded that this investigation should be performed on all patients undergoing cholecystectomy.
The 4‐day Telepaque test demonstrated stones in the gall‐bladder in 30 per cent of the patients with a non‐functioning gall‐bladder on oral cholecystography, thus materially improving the diagnosis of gall‐bladder stones preoperatively. Of duct stones, however, only 32 per cent were shown by the 4‐day Telepaque test, and 59 per cent were demonstrated by intravenous cholangiography. In view of the risk associated with Biligrafin, and to a lesser extent with large doses of Telepaque, it is concluded that neither of these tests is desirable prior to cholecystectomy in the good‐risk patient, provided that a satisfactory technique of operative cholangiography is used. They should be reserved for the poor‐risk patient, when the presence or absence of duct stones may influence the decision to operate.