Op0299 in Rheumatoid Arthritis Patients Higher Number of Comorbidities Predicts 6-Month Insufficient Response to First Biologic Therapy and Eventual Categorization of the Disease as Difficult-to-Treat
Abstract:Background:Difficult-to-treat rheumatoid arthritis (D2T RA) was recently defined by a EULAR study group (1) and, as a disease category it is largely complicated and under-researched. Patient comorbidities may play a significant role in the response to therapy with biologic disease-modifying antirheumatic drugs (bDMARDs) and in the disease classification as D2T RA.Objectives:To evaluate the impact of comorbidities [studied as total Comorbidities Count (CC) and rheumatic disease comorbidity index (RDCI)] on 6-mo… Show more
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