Abstract:BackgroundIn about 10% of patients, the immune response to immune checkpoint inhibitors (ICI) exceeds the anti-tumor response and leads to autoimmune complications (immune-related Adverse Events, irAEs), which can sometimes be severe and require the use of targeted therapies. Two studies recently reported a deleterious impact of targeted therapies on the survival of patients with irAEs.ObjectivesTo compare overall survival in patients treated or not with a biological or targeted synthetic DMARD (b/tsDMARD) for… Show more
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