Oocyte Maturation in Humans: the Potential Relevance to Reproductive Medicine

Yoshimura, Yasunori

doi:10.1274/jmor.20.86

Cited by 1 publication

(1 citation statement)

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“…Additionally, IVM might provide a valuable model for investigating the causes of meiotic aberrations and aneuploidies that are remarkably common in mature human oocytes. Finally, IVM might open the door to oocyte cryopreservation if the freeze storage of germinal vesicle (GV) stage oocytes avoids the problem of damaging the meiotic spindle of metaphase II (MII) stage oocytes 1 . Therefore, IVM is an important technique for assisted reproductive technology and deserves rigorous experimental evaluation to determine whether it is practicable in reproductive medicine.…”

Section: Introductionmentioning

confidence: 99%

Cryopreservation and in vitro maturation of germinal vesicle stage oocytes of animals for application in assisted reproductive technology

Yamanaka

Aono²,

Yoshida³

et al. 2007

Reprod Medicine & Biology

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Cryopreservation, in vitro maturation, fertilization and culture can be applied to various processes across a wide range of species, that is, for the breeding and reproduction of farm animals, preservation of genetic variants in laboratory animals, and the conservation of wild species. In particular, the storage of oocytes by cryopreservation and IVM following cryopreservation, might become effective alternative assisted reproduction treatments for infertile patients. For example, in a clinical context, these techniques might be important for patients who are at risk of losing their ovarian function because of extirpative therapy, chemotherapy or radiation. Thus, it is important for assisted reproductive technology to improve IVM and cryopreservation techniques. In the present review, we introduce our recent studies on vitrification and IVM of germinal vesicle stage oocytes in animals. (Reprod Med Biol 2007; 6: 61-68)

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Section: Introductionmentioning

confidence: 99%