Oocyte maturation: Converting the zebrafish oocyte to the fertilizable egg

Lessman, Charles A.

doi:10.1016/j.ygcen.2008.11.004

Cited by 46 publications

(33 citation statements)

References 38 publications

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“…Fsh stimulates estradiol production, which in turn leads to a surge in Lh hormone levels, which, through its receptor (Lhcgr; Patino et al 2001, Clelland & Peng 2009), stimulates the production of maturation-inducing hormone and through its receptors (progestin and adipoQ receptor, namely Paqr7b and Paqr8) activate the oocyte maturation processes (Hanna & Zhu 2009). In addition, the transforming growth factor b (Tgfb) superfamily also plays a role in regulating oocyte maturation (Clelland et al 2006, Halm et al 2008, Clelland & Peng 2009, Lessman 2009, Tan et al 2009), which includes activin-A, bone morphogenetic protein-15 (Bmp15), Tgfb1, and growth and differentiation factor 9 (Gdf9).…”

Section: Introductionmentioning

confidence: 99%

Comparison of fecundity and offspring immunity in zebrafish fed Lactobacillus rhamnosus CICC 6141 and Lactobacillus casei BL23

Qin

Xu²,

Yang³

et al. 2014

Reproduction

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To increase the knowledge of probiotic effects on zebrafish (Danio rerio), we compare the effects of two probiotic strains, Lactobacillus rhamnosus CICC 6141 (a highly adhesive strain) and Lactobacillus casei BL23 (a weakly adhesive strain), on zebrafish reproduction and their offsprings' innate level of immunity to water-borne pathogens. During probiotics treatments from 7 to 28 days, both the Lactobacillus strains, and especially L. casei BL23, significantly increased fecundity in zebrafish: higher rates of egg ovulation, fertilization, and hatching were observed. Increased densities of both small and large vitellogenic follicles, seen in specimens fed either Lactobacillus strain, demonstrated accelerated oocyte maturation. Feeding either strain of Lactobacillus upregulated gene expression of leptin, kiss2, gnrh3, fsh, lh, lhcgr, and paqr8, which were regarded to enhance fecundity and encourage oocyte maturation. Concomitantly, the gene expression of bmp15 and tgfb1 was inhibited, which code for local factors that prevent oocyte maturation. The beneficial effects of the Lactobacillus strains on fecundity diminished after feeding of the probiotics was discontinued, even for the highly adhesive gut Lactobacillus strain. Administering L. rhamnosus CICC 6141 for 28 days was found to affect the innate immunity of offspring derived from their parents, as evinced by a lower level of alkaline phosphatase activity in early larval stages. This study highlights the effects of probiotics both upon the reproductive process and upon the offsprings' immunity during early developmental stages.

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Section: Introductionmentioning

confidence: 99%

Comparison of fecundity and offspring immunity in zebrafish fed Lactobacillus rhamnosus CICC 6141 and Lactobacillus casei BL23

Qin

Xu²,

Yang³

et al. 2014

Reproduction

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“…Oogenesis (Fig. 3), including final meiotic maturation and ovulation, is under the control of the hypothalamus-pituitary-gonadal axis and involves the production of estradiol 17b and 17a,20b-dihydroxyprogesterone by the follicle wall that, respectively, in turn, elicits vitellogenesis and cyclin b production and the reinitiation of meiosis from the prophase I block (Selman et al, 1993;Selman et al, 1994;Lessman, 1999Lessman, , 2009. Oogenesis is further complicated by the oocyte growth required to stockpile maternal determinants, RNA stores, nutrient (yolk) stores, and all other resource materials to allow the independent development of the embryo for the first 6 to 7 days until feeding begins.…”

Section: Fish Husbandry Considerationsmentioning

confidence: 99%

“…The fully grown follicle is stimulated by gonadotropin, the follicle wall produces 17a, 20b-dihydroxy progesterone (DHP), that elicits cyclin b production and progression of the cell cycle (maturation) to metaphase II. Prominent changes during meiotic maturation include germinal vesicle dissolution (GVD) of the nucleus (germinal vesicle, GV), blastodisc formation at the animal pole, and clearing of the yolky ooplasm (Selman et al, 1993(Selman et al, , 1994Lessman et al, 2007;Lessman, 2009). Finally, the follicle wall ruptures during ovulation and oviposition follows during spawning.…”

Section: Fish Husbandry Considerationsmentioning

confidence: 99%

The developing zebrafish (Danio rerio): A vertebrate model for high‐throughput screening of chemical libraries

Lessman

2011

Birth Defects Research Pt C

Self Cite

136

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The zebrafish, Danio rerio, a small, tropical freshwater species native to Pakistan and India, has become a National Institutes of Health-sanctioned model organism and, due to its many advantages as an experimental vertebrate, it has garnered intense interest from the world's scientific community. Some have labeled the zebrafish, the "vertebrate Drosophila," due to its genetic tractability, small size, low cost, and rapid development. The transparency of the embryo, external development, and the many hundreds of mutant and transgenic lines available add to the allure. Now it appears, the zebrafish can be used for high-throughput screening (HTS) of drug libraries in the discovery process of promising new therapeutics. In this review, various types of screening methods are briefly outlined, as are a variety of screens for different disease models, to highlight the range of zebrafish HTS possibilities. High-content screening (HCS) has been available for cell-based screens for some time and, very recently, HCS is being adapted for the zebrafish. This will allow analysis, at high resolution, of drug effects on whole vertebrates; thus, whole body effects as well as those on specific organs and tissues may be determined.

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“…Then at the appropriate time, depending on the sex of the organism, the process of gametogenesis (spermatogenesis if male and oogenesis if female) is initiated to generate fully mature gametes that are capable of producing the next generation upon fertilization. Oogenesis in zebrafish and medakafish has been recently reviewed (Clelland and Peng, 2009; Lessman, 2009; Saito and Tanaka, 2009). In the next section, we review the process of spermatogenesis.…”

Section: Germline Developmentmentioning

confidence: 99%