Oocyte Follicle Cells Association during Development of Human Ovarian Follicle. A Study by High Resolution Scanning and Transmission Electron Microscopy.

Motta, Pietro M.; Makabe, S; Naguro, Tomonori; Correr, S

doi:10.1679/aohc.57.369

Cited by 123 publications

(114 citation statements)

References 38 publications

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“…10A) is accompanied by satellite cells (black arrow) substituting granulosa cell derived Balbiani body in providing additional organelles (black arrowhead) needed by the developing egg. To greatly increase a volume of the oocyte, the human granulosa cell microvilli penetrate in vivo deep into the ooplasm of developing oocytes and supply a variety of organelles such as Golgi vesicles, endoplasmic reticulum membranes, and nascent forms of smooth endoplasmic reticulum (Motta et al, 1994).…”

Section: Development Of Oocytes and Parthenogenetic Embryos In Vitromentioning

confidence: 99%

Ovarian Stem Cell Niche and Follicular Renewal in Mammals

Bukovský

2011

The Anatomical Record

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Stem cell niche consists of perivascular compartment, which connects the stem cells to the immune and vascular systems. During embryonic period, extragonadal primordial germ cells colonize coelomic epithelium of developing gonads. Subsequently, ovarian stem cells (OSC) produce secondary germ cells under the influence of OSC niche, including immune system-related cells and hormonal signaling. The OSC in fetal and adult human ovaries serve as a source of germ and granulosa cells. Lack of either granulosa or germ cell niche will result in premature ovarian failure in spite of the presence of OSC. During perinatal period, the OSC transdifferentiate into fibroblast-like cells forming the ovarian tunica albuginea resistant to environmental threats. They represent mesenchymal precursors of epithelial OSC during adulthood. The follicular renewal during the prime reproductive period (PRP) ensures that there are fresh eggs available for a healthy progeny. End of PRP is followed by exponentially growing fetal genetic abnormalities. The OSC are present in adult, aging, and postmenopausal ovaries, and differentiate in vitro into new oocytes. During in vitro development of large isolated oocytes reaching 200 lm in diameter, an ancestral mechanism of premeiotic nurse cells, which operates during oogenesis in developing ovaries from invertebrates to mammalian species, is utilized. In vitro developed eggs could be used for autologous IVF treatment of premature ovarian failure. Such eggs are also capable to produce parthenogenetic embryos like some cultured follicular oocytes. The parthenotes produce embryonic stem cells derived from inner cell mass, and these cells can serve as autologous pluripotent stem cells. Anat Rec, 294:1284Rec, 294: -1306Rec, 294: , 2011. V V C 2011 Wiley-Liss, Inc.

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Section: Development Of Oocytes and Parthenogenetic Embryos In Vitromentioning

confidence: 99%

Ovarian Stem Cell Niche and Follicular Renewal in Mammals

Bukovský

2011

The Anatomical Record

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“…The studies of Motta et al (1994) on human ovarian follicles were the first to demonstrate that dynamic alterations in the number and form of TZPs occur at specific stages of follicle development and might serve to co-ordinate or modulate information exchange between the oocyte and follicle cells. This work showed that, in preantral follicles, TZPs were most numerous forming both adhesive and gap junctional contacts at the oolemma, and further demonstrated that during peak periods of oocyte growth, TZPs extended as deep invaginations that impinged upon the germinal vesicle.…”

Section: Transzonal Projections At the Oocyte-granulosa Cell Boundarymentioning

confidence: 99%

Cellular basis for paracrine regulation of ovarian follicle development

Albertini

Combelles²,

Benecchi³

et al. 2001

Reproduction

477

215

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Although the physiological, molecular and genetic determinants that initiate and sustain follicular growth and maturation have received much attention (see reviews by McNatty et al., 1999;McGee and Hsueh, 2000), comparatively little information has been forthcoming with regard to the changes in cellular behaviour that attend the process of folliculogenesis. When viewed in the context of other developmental systems, in which paracrine control of cell differentiation is considered implicitly relative to cell signalling, cell-cell adhesion and cell-extracellular matrix (ECM) interactions, our knowledge of cellular behaviours in the ovarian follicle is lacking, despite the wealth of information available on the role of growth factors and hormones in ovarian follicle development (for a review see Elvin and Matzuk, 1998). Recently, Rodgers et al. (1999 have drawn attention to the role of the ECM during bovine follicle growth as related to changes in the follicular basal lamina that may influence the growth and differentiation of both granulosa and theca cells. Given the

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“…TZPs have been described in a wide range of mammals (De Smedt and Szollosi, 1991;De Lesegno et al, 2008). In primates, TZPs have been identified that project deep into the oocyte, reaching even as far as the nucleus (Hope, 1965;Motta et al, 1994;Makabe et al, 2006). Studies such as these unequivocally established the nature of the germ line-soma interaction.…”

Section: Discovery and Description Of Tzpsmentioning

confidence: 99%

History, origin, and function of transzonal projections: the bridges of communication between the oocyte and its environment

Clarke

2018

Anim Reprod

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Development and differentiation of a functional oocyte that following fertilization is able to give rise to a new individual requires continuous physical contact with the supporting somatic cells of the ovarian follicle. As the oocyte is surrounded by a thick extracellular coat, termed the zona pellucida, this essential contact is mediated through thin cytoplasmic filaments known as transzonal projections (TZPs) that project from the somatic granulosa cells adjacent to the oocyte and penetrate through the zona pellucida to reach the oocyte. Gap junctions assembled where the tips of the TZPs contact the oocyte plasma membrane, and other contact-dependent signaling may also occur at these sites. Here, I describe early studies of TZPs, which were first identified in the late 19th century, discuss their similarities with classical filopodia, review their structure and function, and compare two models that could account for their origin. Possible priorities and directions for future studies close this contribution.

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Oocyte Follicle Cells Association during Development of Human Ovarian Follicle. A Study by High Resolution Scanning and Transmission Electron Microscopy.

Cited by 123 publications

References 38 publications

Ovarian Stem Cell Niche and Follicular Renewal in Mammals

Ovarian Stem Cell Niche and Follicular Renewal in Mammals

Cellular basis for paracrine regulation of ovarian follicle development

History, origin, and function of transzonal projections: the bridges of communication between the oocyte and its environment

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