Oocyte Cryopreservation for Elective Preservation of Reproductive Potential

Martinuzzi, Kurt; Copperman, A.B.

doi:10.2174/157340407781387663

Cited by 1 publication

(2 citation statements)

References 25 publications

(33 reference statements)

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“…The pivotal event leading to oocyte cryopresesrvation was becoming aware of advances in this technology. Had they heard that such a technology existed when they were younger, most stated that they would have made use of it [23]. Of the 159 patients who completed the 209 cycles in our study, the mean number of oocytes retrieved was 13.8, yet only 69 cycles (33%) resulted in our goal of ≥10 mature oocytes for cryopreservation.…”

Section: Discussionmentioning

confidence: 96%

“…It is possible that women seeking fertility preservation are either a self-selected population with a family history of diminished ovarian reserve, or may have already noted alterations in their menstrual cycle. In our previous publication on the psychological characteristics of women presenting for elective cryopreservation of oocytes, we have previously reported that most notable was their high level of education and their overwhelming self-description as being "intelligent" and "extroverted" [23]. A number of women said they were interested in egg freezing to take the pressure off the search for relationships.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Elective oocyte freezing for the preservation of fertility

Barritt¹,

Luna²,

Sandler³

et al. 2012

OJOG

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Oocyte cryopreservation has recently emerged as an option for women to preserve their fertility for medical (e.g. treatable malignancy) or elective indications (e.g. advancing age). This report describes an IRB-approved study of over 200 oocyte cryopreservation cycles at one center. Patients presenting for oocyte cryopreservation (January 2005 to 2010) were analyzed for day 3 follicle stimulating hormone (FSH), basal antral follicle count (BAFC), gonadotropin usage and the number of oocytes retrieved and cryopreserved. New patient consultations were performed on 516 women, of whom 175 (34%) proceeded to initiate a total of 233 cryopreservation cycles. Twenty-four cycles were cancelled (10%) after starting follicular stimulation due to poor ovarian response or self-withdrawal of the patients. Patients whose cycles were cancelled demonstrated a higher Day 3 FSH and a lower BAFC than patients who completed cycles (p < 0.01). In the 209 completed cycles, the most important predictors of a successful cycle included BAFC (r = 0.36), FSH (r = –0.25) and age (r = –0.18) with the mean number of oocytes cryopreserved at 13.6 ± 8.8. Information about long-term fertility preservation must reach both patients and health care providers so that more women can be educated about the benefits of proactive early physiological reproductive assessment and possible interventions available

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%