Onychomycosis by Paecilomyces lilacinus in a patient with leukonychia

Innocenti, Patrizia; Pagani, Elisabetta; Vigl, Dunja; Pasquetto, Valentina; Scalzo, Katia; Larcher, Clara

doi:10.4081/mm.2010.2487

Cited by 1 publication

(1 citation statement)

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“…Onycholysis is an interesting cutaneous manifestation, which happens via distal separation of the nail plate from the nail bed (71) that can occur through hyperthyroidism (called Plummer's nails) (22,23) or other mechanisms including psoriasis (72), certain cancer drugs (73), fungal and bacterial infections (74), and direct trauma (71). Plummer was the first to describe Plummer's nails when he drew attention to this manifestation of onycholysis in patients with hyperthyroidism (75).…”

Section: Nails Onycholysismentioning

confidence: 99%

Dermatologic manifestations of thyroid disease: a literature review

2023

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IntroductionThyroid hormone is considered one of the key regulatory hormones for skin homeostasis. Multiple organs are affected by the release of peripheral thyroid hormones (T4 and T3) further regulating various functions at a cellular level. Specifically, skin is considered an important target organ in which the thyroid hormone has a significant impact. Multiple skin diseases are associated with thyroid hormone dysregulation. However, other striking dermatologic manifestations are seen in nails and hair as well. Hypothyroidism, hyperthyroidism, and thyroid cancer can have an array of cutaneous manifestations, and we present the recent updates in this field.MethodsA PubMed search was performed for updates in any new skin disease findings and treatments between 2010 and 2022. Research published in the past decade and previously known foundational skin findings associated with thyroid disease were presented in this review.ConclusionCutaneous manifestations of thyroid disease is one of the first notable signs of thyroid hormone dysregulation. This article reviews the recent updates on the thyroid and skin interplay, and it further discusses overt visible findings and various available treatment modalities.

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