Ontogenetic development of Anastrepha fraterculus (Diptera: Tephritidae): Isoenzyme patterns of isocitrate and alcohol dehydrogenases

Nascimento, Jurema Cruz do; Oliveira, Alice Kalisz de

doi:10.1016/s0300-9629(97)00038-8

Cited by 3 publications

(1 citation statement)

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“…The ADH system of Anastrepha is similar to that of Drosophila in its electrophoretic patterns, the dimeric composition of the functional enzyme and the differential tissue and life stage expression of loci ( Matioli et al , 1986 , 1992 ; Nascimento and Oliveira, 1997 ). Their ADH enzymes seem to have evolved independently although from a common ancestral gene ( Ashburner, 1998 ).…”

Section: Introductionmentioning

confidence: 99%

Alcohol dehydrogenase activities and ethanol tolerance in Anastrepha (Diptera, Tephritidae) fruit-fly species and their hybrids

2009

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The ADH (alcohol dehydrogenase) system is one of the earliest known models of molecular evolution, and is still the most studied in Drosophila. Herein, we studied this model in the genus Anastrepha (Diptera, Tephritidae). Due to the remarkable advantages it presents, it is possible to cross species with different Adh genotypes and with different phenotype traits related to ethanol tolerance. The two species studied here each have a different number of Adh gene copies, whereby crosses generate polymorphisms in gene number and in composition of the genetic background. We measured certain traits related to ethanol metabolism and tolerance. ADH specific enzyme activity presented gene by environment interactions, and the larval protein content showed an additive pattern of inheritance, whilst ADH enzyme activity per larva presented a complex behavior that may be explained by epistatic effects. Regression models suggest that there are heritable factors acting on ethanol tolerance, which may be related to enzymatic activity of the ADHs and to larval mass, although a pronounced environmental effect on ethanol tolerance was also observed. By using these data, we speculated on the mechanisms of ethanol tolerance and its inheritance as well as of associated traits.

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Section: Introductionmentioning

confidence: 99%