Onset of hydronephrosis and lower urinary tract symptoms in a previously healthy young man: Phyllodes tumour of the prostate as a potential diagnosis.

Abstract

Cite as: Can Urol Assoc J 2014;8(7-8):e561-3. http://dx.doi.org/10.5489/cuaj.1984 Published online August 11, 2014. AbstractWe report the case of a 50-year-old healthy man with early onset of micturition symptoms associated with an elevated total prostatespecific antigen. On physical examination, we found an enlarged prostate; a first-line ultrasound of the urinary tract revealed local disease which covered the entire small pelvis. A computed tomography scan confirmed the presence of a 12.5 × 11.0 × 9.5-cm multicystic prostatic mass, compressing the bladder and pelvic ureters, associated with right hydronephrosis. Renal function was preserved and prostatic biopsies was negative for malignant disease. The mass was completely removed through transvesical approach and histological analysis diagnosed a low-grade phyllodes tumour of the prostate. The patient was free of local recurrence and metastasis 36 months after surgery.

Phyllodes tumor of the verumontanum: a case report

“…Phyllodes tumors are rare even in the breast, where they account for less than 1 % of all neoplasms [ 1 ]. Ferrariet et al proposed that phyllodes tumor of the prostate is a potential diagnosis for previously healthy young men with hydronephrosis and lower urinary tract symptoms [ 3 ]. The patient described here presented with salient difficult urination.…”

Hydronephrosis alters cardiac ACE2 and Mas receptor expression in mice

“…Chronic kidney disease such as hydronephrosis is a severe worldwide problem and causes an increase in cardiovascular risk. [1][2][3][4][5] The renal vasoactive system controlling blood pressure and the renin-angiotensin system (RAS) was postulated to be involved in the hypertension implicated in hydronephrosis. [6][7][8] Hydronephrotic hypertension has often been explained to be caused by the RAS activated in the kidney leading to high blood pressure.…”