Onset of estrus and preovulatory LH surge and ovulatory efficiency in sheep after short‐term treatments with progestagen‐sponges and progesterone‐CIDRs

Martínez-Ros, Paula; Astiz, Susana; García-Roselló, E.; Rios-Abellan, Alejandro; González-Bulnes, Antonio

doi:10.1111/rda.13317

Cited by 8 publications

(8 citation statements)

References 15 publications

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“…Still, other studies used progestogen-based protocols during seven days in the breeding season, with similar conception rates (75%) in dairy ewes [14] or greater conception rates (87%) in meat sheep [21]. In addition, short-term exposure to progestogens has also been described using different devices (CIDR ® ) 3 and with good conception rates being reached [13][14][15]20,21]. So, a short-term treatment with progestogens proved to be equally effective for inducing estrus behavior, preovulatory LH discharge, and ovulation in sheep [13], resulting in a good concept rate, probably due to the ovulation of newly recruited growing follicles [21].…”

Section: Discussionmentioning

confidence: 99%

“…In addition, short-term exposure to progestogens has also been described using different devices (CIDR ® ) 3 and with good conception rates being reached [13][14][15]20,21]. So, a short-term treatment with progestogens proved to be equally effective for inducing estrus behavior, preovulatory LH discharge, and ovulation in sheep [13], resulting in a good concept rate, probably due to the ovulation of newly recruited growing follicles [21]. Therefore, considering not only its efficiency but also the reduction of damage to the vaginal microbiota, we strongly encourage the use of the 6-day synthetic progesterone exposure protocol [14].…”

Section: Discussionmentioning

confidence: 99%

“…Nevertheless, it has been reported that long-term treatments can cause vaginitis and affect viability of ram sperm, as well as prolong lifespan of large follicles, releasing an older oocyte with less chance of being fertilized [9,10,21]. On the other hand, studies have demonstrated that short-term treatments can induce cyclic activity during seasonal anestrous in meat ewes [13,19,20].…”

Section: Introductionmentioning

confidence: 99%

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Hormonal Protocols for the Synchronization and Induction of Synchronized Estrus in Dairy Ewes Kept under Tropical Conditions

Lombardo

Monteiro

Delgado

et al. 2020

Acta Scientiae. Vet.

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Background: Lacaune is an important sheep breed and shows reproductive seasonality which affects dairy product supply. The most common hormonal protocols are based on progesterone-releasing devices in order to reach reproductive activity. Due to international consumer demand for natural, green, and clean methods, such issues encourage the minimal or absent use of synthetic hormones in livestock. In this sense, the present study tested the efficiency of induction and estrus synchronization protocols in lacaune ewes, considering: application interval of synthetic prostaglandin at the breeding season; length of synthetic progesterone exposure; and eCG dose at the outbreeding season.Materials, Methods & Results: In study 1, 52 ewes were submitted to estrus synchronization protocol using two doses of d-cloprostenol 7 or 9 days apart. In study 2, 47 ewes were submitted to estrus induction protocol using an intravaginal device containing 60 mg of medroxyprogesterone acetate maintained for 6, 9, or 12 days. In study 3, 46 ewes were submitted to synchronized estrus induction protocol using intravaginal progesterone device for six days. On the fifth day, d-cloprostenol and 300 IU or 400 IU of eCG were administered. For all studies, signs of estrus beginning/ending were recorded and natural mating was performed. After 30 days, transrectal ultrasound was performed for pregnancy diagnosis. In study 1, groups presented similar rate of estrus behavior (78.8%) and pregnancy (average 75.6%). Meanwhile, compared to G9days (37.8 ± 7.2 h), interval between the second dose of prostaglandin and beginning of estrus was smaller in G7days (31.5 ± 7.8 h). No difference was found among variables studied in study 2 (P > 0.05), nevertheless the SD for the estrus duration was shorter (P < 0.05) in G6days and G12 days when compared with the G9days. Equally, the SD for the interval between sponge withdrawal and beginning and end of estrus was shorter (P < 0.05) in G12days when compared with the G9days. The pregnancy rate, at 30 days, was 71.1%. With regards to study 3, there was no effect of parturition order on sexual behavior between experimental groups (P > 0.05). Equally, no differences were found between variables studied (P > 0.05). The pregnancy rate was 52.2% and number of concepts was 1.5 ± 0.6.Discussion: This paper provides important data on estrus synchronization protocols in dairy sheep kept under tropical conditions. In study 1, both d-cloprostenol protocols were efficient in synchronizing estrus of dairy ewes and reached a fair pregnancy rate. Therefore, it was demonstrated that a d-cloprostenol treatment was a viable alternative to a progestogen treatment, commonly used for estrus synchronization in ewes even during the breeding season. In study 2, all protocols (6, 9 and 12 days of exposure to synthetic progesterone) were efficient in inducing and synchronizing estrus in dairy ewes during the outbreeding season. Therefore, considering not only its efficiency but also the reduction of damage to the vaginal microbiota, the authors strongly encourage the use of the 6-day synthetic progesterone exposure protocol. The third study showed that it is possible to reduce the eCG dose (400 to 300 IU) in dairy ewes while maintaining protocol efficiency, saving 25% of the farmer spending, and avoiding high doses that are related to immune resistance and lower progressive fertility response to IA. In conclusion, the present study verified the efficiency of different hormonal protocols applied for dairy Lacaune ewes kept under tropical conditions, demonstrating that it is possible to decrease: (i) the interval between prostaglandin applications for 7 days apart during the breeding season; (ii) the length of exposure to synthetic progesterone for 6 days; and (iii) the eCG dose to 300 IU during the outbreeding season.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Hormonal Protocols for the Synchronization and Induction of Synchronized Estrus in Dairy Ewes Kept under Tropical Conditions

Lombardo

Monteiro

Delgado

et al. 2020

Acta Scientiae. Vet.

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“…La sincronización del estro con dispositivos de liberación controlada de fármacos (CIDR) se ha usado con eficiencia en varias especies animales: vacas (Bonacker et al, 2020), búfalas (Neglia et al, 2020), cabras (Skliarov et al, 2021) y ovejas (Gonzalez-Bulnes et al, 2020. Los CIDR para ovejas están impregnados con 0,3 g de progesterona natural (Wheaton et al, 1993), y generalmente son aplicados en protocolos largos de 12 a 14 días (Viñoles et al, 2001) y algunos estudios los han evaluado bajo protocolos de corta duración de 5-7 días (Menchaca y Rubianes, 2004;Martinez-Ros et al, 2019. En estos últimos se ha observado una mejor sincronización del estro y buena fertilidad con IA en ovejas comparado con protocolos largos (Cox et al, 2012;Dias et al, 2015;Santos-Neto et al, 2015;Martínez-Ros et al, 2020).…”

Section: Introductionunclassified

Los dispositivos reutilizados en protocolos cortos de sincronización tienen el mismo efecto sobre el desempeño reproductivo y perfiles de progesterona en ovejas Pelibuey

Luna-Palomera¹,

Macías‐Cruz²,

Sánchez-Dávila³

et al. 2022

ITEA

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El objetivo fue evaluar la conducta estral, tasa de preñez y niveles de P4 en ovejas Pelibuey tratadas bajo un protocolo de sincronización del estro de corta duración con dispositivos intravaginales nuevos (CIDRn) y reusados (CIDR1, CIDR2). Se evaluó el porcentaje de ovejas en estro, intervalo retiro dispositivo-estro, duración del estro, porcentaje de gestación y porcentaje de dispositivos retenidos; así como los niveles de P4 los días -10 (inserción), -8, -6, -2 (retirada) y 0 (día del estro). Las variables categóricas fueron analizadas por Chi-cuadrado, las variables continuas por análisis de varianza y los niveles de P4 por medidas repetidas en el tiempo. No se observaron diferencias (P > 0,05) entre las ovejas tratadas con CIDRn, CIDR1 y CIDR2 en ninguna de las variables reproductivas analizadas. Se concluye que la liberación de P4 remanente en los dispositivos reutilizados es suficiente para lograr una adecuada sincronización del estro y tasa de preñez en ovejas Pelibuey.

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“…The device inhibits GnRH secretion and consecuently prevents the release of gonadotropins, especially luteinizing hormone (LH; Rubianes, 2003). Once the device is removed, an injection of equine chorionic gonadotropin (eCG) is applied (Abecia et al, 2011), which has an effect of follicle-stimulating hormone (FSH) and LH to enhance ovulation (Quintero-Elisea et al, 2011;Martinez-Ros et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Estrous synchronization in sheep with reused progesterone devices and eCG

López-García¹,

Sánchez-Torres²,

Cordero-Mora³

et al. 2021

Revista Brasileira De Zootecnia

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The objective of the present research was to determine the effect of long synchronization protocols based on reused progesterone devices (controlled internal drug release [CIDR]) associated with different doses of equine chorionic gonadotropin (eCG) on reproductive variables in crossbred sheep (Suffolk × Kathadin × Dorset). The CIDR were used for eleven days in a previous study in sheep from the same herd and were washed and disinfected before reusing. Sixty-four sheep, in the reproductive season, were randomly assigned to four experimental groups (n = 16). Treatments consisted of a group with 10 d CIDR and 300 IU eCG; a group with 10 d CIDR and 400 IU of eCG; a group with 12 d CIDR and 300 IU of eCG; and a group with 12 d CIDR and 400 IU of eCG. A completely randomized design was used. There was an estrous presentation rate of 100% in all treatments. The begining of estrous, gestation rate, fertility rate, type of parturition, and prolificacy index were equal between groups. Progesterone serum concentration was higher in sheep from the 10 d CIDR groups. The CIDR, reused for the second time, associated with 300 or 400 IU of eCG for estrous synchronization in sheep, are effective to obtain good pregnancy rates and ensures higher prolificacy rates.

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Onset of estrus and preovulatory LH surge and ovulatory efficiency in sheep after short‐term treatments with progestagen‐sponges and progesterone‐CIDRs

Cited by 8 publications

References 15 publications

Hormonal Protocols for the Synchronization and Induction of Synchronized Estrus in Dairy Ewes Kept under Tropical Conditions

Hormonal Protocols for the Synchronization and Induction of Synchronized Estrus in Dairy Ewes Kept under Tropical Conditions

Los dispositivos reutilizados en protocolos cortos de sincronización tienen el mismo efecto sobre el desempeño reproductivo y perfiles de progesterona en ovejas Pelibuey

Estrous synchronization in sheep with reused progesterone devices and eCG

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