The proximity between nasal and sinus structures and the orbit causes ocular complications to occur with some frequency in endoscopic sinus surgery (ESS). Among them, vascular ones are rare. Only 3 cases of post-ESS retinal artery obstruction have been published to date. Despite the low frequency, arterial occlusions can cause irreversible damage to vision. In the present report, we present a case of a patient who evolved with occlusion of the cilioretinal artery, leading to scotoma formation in the left eye, after ESS. The present report highlights the importance of the otolaryngologist's knowledge of this complication, which, although rare, has high morbidity.