The rise of virtual organizations has brought a significant transformation in the way businesses and non-profit organizations operate. This paper provides an overview of a virtual organizations management, effective virtual team management strategies, and the impact of virtualization on non-profit organizations. The study finds that virtual organizations offer several benefits, including flexibility, adaptability, and costeffectiveness, along with easy access to a pool of freelancers who can perform various types of work. However, effective communication, coordination, and a culture of trust, accountability, and collaboration are essential for their success. The research also examines online interventions in non-profit organizations, specifically the virtual day center, which provides a safe and relaxed space for young people to meet and talk. The study suggests that online interventions can be implemented in harm reduction programs and can increase substance abuse prevention efforts.