Online capillary solid-phase microextraction coupled liquid chromatography-mass spectrometry for analysis of chiral secondary alcohol products in yeast catalyzed stereoselective reduction cell culture

Sequential chemo–biocatalytic synthesis of aroma compounds

“…The reduction of benzalacetone by S. cerevisiae had been used as a model reaction before, with the production of S -4-phenyl-2-butanol in 92.9% ee and a high yield (82.3%) after 4 days of biotransformation under specified conditions. 54…”