One-year visual outcomes and patient satisfaction after surgical correction of presbyopia with an intracorneal inlay of a new design

Abstract

The new corneal inlay was a safe and effective treatment for presbyopia over a 1-year follow-up.

Reading performance and patient satisfaction after corneal inlay implantation for presbyopia correction: Two-year follow-up

“…The surgical procedure has been described in detail. 15 The inlay is made of polyvinylidene fluoride with nanoparticles of carbon incorporated to make it opaque. It has 8400 laser-drilled porosity holes (diameter 5 to 11 mm) arranged in a pseudorandomized pattern to allow sufficient nutritional flow through the inlay to sustain the viability of the anterior stromal lamella and to prevent corneal thinning and epithelial problems.…”

“…The development of materials with enhanced biocompatibility, 7,8 advances in technology such as femtosecond lasers, and a better understanding of physiology and the wound-healing response have allowed corneal inlay technology to mature. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] Currently available presbyopia-correcting corneal inlays are based on creating a hyperprolate cornea by inserting a space-occupying inlay (VueC, Revision Optics, Inc.), 13 generating a bifocal optic by implanting refractive annular addition lenticules (Flexivue Q 2012 ASCRS and ESCRS 0886-3350/$ -see front matterPublished by Elsevier Inc. http://dx. …”

“…[10][11][12][13][14][15][16][17] Since approval by the authorities of the Conformit ee Europ eenne (CE-mark) in 2005, refractive surgeons have been able to implant the Kamra corneal inlay outside clinical trials on a commercial basis, whereas the technique is still under investigation in U.S. Food and Drug Administration (FDA) clinical trials for the treatment of near-plano and plano presbyopia. [10][11][12][13][14][15][16][17] Designed to increase the depth of focus based on the principle of small-aperture optics, the corneal inlay was designed to improve uncorrected near and intermediate vision while minimally affecting distance vision. 10 Mid-term and long-term studies support the efficacy and safety of this inlay for the treatment of presbyopia, with published data for up to 4 years.…”

“…10 Mid-term and long-term studies support the efficacy and safety of this inlay for the treatment of presbyopia, with published data for up to 4 years. [10][11][12][14][15][16][17] The main intention of the Kamra corneal inlay is to improve uncorrected near vision; thus, the assessment of reading performance is considered to be the most important clinical examination for evaluating the benefits of this presbyopia treatment. 12,14 The Salzburg Reading Desk measures reading performance using computerized testing under standardized conditions while simulating a natural reading process.…”

Structural Changes Induced by a Corneal Shape-Changing Inlay, Deduced From Optical Coherence Tomography and Wavefront Measurements

“…The US Food and Drug Administration (FDA)-approved KAMRAInlay (Acufocus, Irvine, CA, USA) extends depth-of-focus from distance through near, by placing a pin-hole (1.6 mm diameter) in an annular disk of diameter 3.8 mm, at the center of the visual axis. 4 The Flexivue Microlens (Presbia, Irvine, CA, USA) inlay is a donut-shaped, high-refractive-index lens that provides distance vision through its central zone (1.6 mm diameter) and the pupillary periphery outside the inlay, and near vision though the curved portion of the 3.2-mm-diameter inlay. 5 The Flexivue Microlens is currently in an FDA clinical trial.…”