One‐year study of the efficacy of a dentifrice containing zinc citrate and triclosan to maintain gingival health

Abstract

– In a previous study we demonstrated that gingival health could be maintained in a group of highly motivated nurses using a dentifrice containing a zinc salt and triclosan. We have now investigated the effect of the experimental dentifrice on a group of less motivated men. One hundred and three male students were given oral hygiene instruction (OHI) and their teeth were professionally cleaned. For each individual, both the instruction and cleaning were completed in a single 15‐min period. Two balanced groups were formed, based on the prestudy plaque levels and gingival bleeding. One group used the experimental dentifrice for 12 months, while the other used a control. Results were assessed after 6 months, and after 12 months. As a result of the OHI, plaque and gingival bleeding were reduced at the end of the prestudy period. This improvement was not maintained by the control group even for 6 months. In contrast, the test group exhibited significantly lower plaque levels and higher standard of gingival health throughout the 12 months. Reassessment of available participants 6 months after the study showed that gingival health in both groups had returned to its prestudy condition. The lower observed standard of gingival health in the test group after ceasing to use the experimental dentifrice further supports the conclusion that this dentifrice can contribute to an oral care program.

Six‐month study of the effect of a dentifrice containing zinc citrate and triclosan on plaque, gingival health, and calculus

“…The study design was similar to that described previously (3). The study design was similar to that described previously (3).…”

Prevention. Part 4: Toothbrushing: What advice should be given to patients?

“…The effectiveness of triclosan formulations has been improved by either adding a copolymer to enhance its retention in the mouth or by adding zinc citrate to provide additional antibacterial activity. These formulations have been shown in randomised controlled trials (Type 2) to provide significant reductions in plaque and significant improvements in gingival health 58,59 when compared with a fluoride toothpaste alone. In studies of 3 years duration the triclosan/copolymer formulation was reported to reduce the onset of periodontitis in adolescents 60 and the further progression of periodontitis in at-risk adults.…”

Dentifrices; an update

“…Systematic reviews of six-month clinical studies have concluded that formulations containing triclosan and copolymer significantly improve plaque control and periodontal health (15)(16)(17). Toothpastes containing triclosan and zinc citrate are also effective in improving plaque control and gingival health (18)(19)(20)(21).…”