One Year Study of Bacterial and Fungal Nosocomial Infections among Patients in Pediatric Intensive Care Unit (PICU) in Alexandria

Abstract

NIs rate was high (23 per cent) mainly due to severity of condition on admission as shown by high PRISM III score value, the high PRISM III score, LOS and referral from wards were predictors of acquisition of NIs and there is a high incidence of Candida albicans infection (10 per cent of NIs).

Risk factors for healthcare-associated infection in pediatric intensive care units: a systematic review

“…Being a patient in the post-operative period was a risk factor in the analysis of Singh-Naz et al 50 and Figueiredo 54 . This variable was not significant in the final model of Gilio et al 51 and was not studied by El-Nawawy et al 52 .…”

“…Abstracts for which there was no agreement as to the inclusion were analyzed jointly and the decision was made by consensus. Thus, 84 (80 articles and four theses) were ob-tained for detailed reading by the same two authors independently 27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,…”

“…The upper age limit found was 18 years. In these studies, the main outcomes were hospital infection in any site 50,51,52,54 , laboratory-confirmed bloodstream infection 55,56,57 , lower respiratory tract infection 58,59,60 and urinary tract infection 49 . All but one article 49 achieved the maximum score of the Newcastle-Ottawa Scale for cohort studies.…”

“…Four selected studies had healthcare-associated infection without a specific site as the main outcome 50,51,52,54 . These reported an incidence of healthcare-associated infection episodes ranging from 10 to 33%.…”

“…Regarding disease severity as assessed by PRISM, Singh-Naz et al 50 and El-Nawawy et al 52 found a significant association to healthcare-associated infection (the latter used the PRISM III). Singh-Naz et al 50 considered the mean PRISM score of the patients for the analysis, whereas Gilio et al 51 , who categorized the scores into fourunit intervals, found no significant association.…”