One‐year results of the Variation of Orthokeratology Lens Treatment Zone (VOLTZ) Study: a prospective randomised clinical trial

Guo, Biyue; Cheung, Sin Wan; Kojima, Randy; Cho, Pauline

doi:10.1111/opo.12834

Cited by 55 publications

(84 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Despite its retrospective design in nature, this was the first study directly investigating the relationship between orthokeratology lens design (especially back optical zone diameter) and myopia control efficacy in children and juveniles, which opened a possibility of optimizing orthokeratology lens designs for better myopia control efficacy. Recently, Guo et al 25 also reported that children wearing orthokeratology lenses with smaller (5.0 mm) back optical zone diameter had significantly slower annual axial elongation (0.04 ± 0.15 mm) as compared with those wearing larger (6.0 mm) back optical zone diameter (0.17 ± 0.13 mm), resulting in a retardation effect of 0.13 mm.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Lens Design on Corneal Power Distribution in Orthokeratology

et al. 2022

View full text Add to dashboard Cite

SIGNIFICANCE: This study will enhance our understanding of the effects of orthokeratology lens design on corneal profile, the results of which may be useful in developing future orthokeratology lens designs.PURPOSE: This study aimed to evaluate the effect of lens design on corneal power distribution after orthokeratology using mathematical methods.METHODS: Sixty-five subjects were enrolled in this prospective study and assigned to four groups: Euclid with 6.2-mm back optic zone diameter (aged <14 years), Euclid with 6.2-mm back optic zone diameter (aged ≥14 years), double tear reservoir lens with 5.0-mm back optic zone diameter, and double tear reservoir lens with 6.0-mm back optic zone diameter. Manifest refraction and corneal topography were checked at baseline and 1 day, 1 week, 2 weeks, and 1 month after lens wear. Relative corneal refractive power change was calculated by a polynomial function and a monomial function. The maximum relative corneal refractive power change (Y max ) and the corresponding distance from the corneal center (X max ) were analyzed. Relative corneal refractive power change over time and between groups was compared using repeated-measures analysis of variance. RESULTS:Refractive reduction and central corneal flattening were seen at all follow-up visits after orthokeratology lens wear, being fastest in the 5.0-mm back optic zone diameter group ( P < .001). The cornea steepened in an aspheric way toward the midperiphery and peaked at approximately 2 to 3 mm off the apex. Overall, Y max was not different among the four groups, but X max was smallest in the 5.0-mm back optic zone diameter group ( P < .001). At 1/2 X max , relative corneal refractive power change of the 5.0-mm back optic zone diameter design was significantly higher than that of the other three groups ( P < .001). The power exponent of the monomial of the 5.0-mm back optic zone diameter design was greater than that of the other three groups ( P < .001).CONCLUSIONS: An orthokeratology lens design with smaller back optic zone diameter might yield a faster myopic reduction and a smaller aspheric treatment zone.

show abstract

Section: Discussionmentioning

confidence: 99%

The Effect of Lens Design on Corneal Power Distribution in Orthokeratology

et al. 2022

View full text Add to dashboard Cite

show abstract

“…A short-term study of different compression factors found that no significant changes in eye parameters were found between the different design lenses [ 28 ]. However, OK lens of smaller back optic zone diameter achieved better curative effect [ 29 , 30 ]. Further investigations will be need to make OK lens more effective in myopia control.…”

Section: Discussionmentioning

confidence: 99%

Factors associated with faster axial elongation after orthokeratology treatment

Liu

et al. 2022

BMC Ophthalmol

View full text Add to dashboard Cite

Background To study the baseline factors that related to faster axial elongation after orthokeratology (OK) treatment and the characteristics of cases with axial length decrease in a group of myopia children. Methods This is a retrospective study. The records of 73 children who had wear OK lens for at least one year were reviewed. Only the data of right eyes were included. Baseline data included: age, gender, parental myopia, refractive error, corneal power, central corneal thickness, axial length and anterior chamber depth. Corneal power, central corneal thickness, anterior chamber depth and axial length after one-year of OK lens wear were also collected. The related factors affecting axial length change were analyzed. A comparison was made on the cases of axial length increase and axial length decrease. Results Of the 73 eyes, axial length increased by 0.18 ± 0.17 mm (P < 0.001) after one year of OK lens wear. Correlation analysis showed that one-year axial length change was negatively correlated with age and positively correlated with the parental myopia and baseline myopia. Stepwise multiple linear regression analysis showed that the factors associated with faster axial elongation were lower baseline myopic spherical equivalent (P = 0.018), higher parental myopia degree (P = 0.026), and younger age at the onset of lens wear. (P = 0.039). Nine eyes showed negative axial growth (−0.06 ± 0.04 mm), and had older initial age of lens wear, higher baseline myopic spherical equivalent, and lager baseline corneal power, when compared with cases of axial length increase. Conclusions Myopia children with lower baseline myopic spherical equivalent, younger initial age and higher parental myopia had faster axial elongation after orthokeratology treatment. More aggressive treatment should be considered. In children with slow axial elongation, OK lens wear may lead to negative axial growth. Whether there are reasons other than central corneal thinning and choroidal thickening needs further study.

show abstract

“…One such design modification is focused on reducing the central treatment zone diameter created on the cornea. [41][42][43] With children being the target population for myopia management using OrthoK, safety is an ever-present concern. Regular and careful follow-up care for OrthoK patients is critical to ensure ongoing corneal health and maintenance of clean lenses.…”

Section: Discussionmentioning

confidence: 99%

“…One such design modification is focused on reducing the central treatment zone diameter created on the cornea. 41–43…”

Section: Discussionmentioning

confidence: 99%

The Role of Orthokeratology in Myopia Management

Lipson¹

2022

Eye &Amp; Contact Lens: Science &Amp; Clinical Practice

View full text Add to dashboard Cite

Intervention to slow axial elongation and progressing degree of myopia has become an important public health issue. Although orthokeratology (OrthoK) has been prescribed to temporarily reduce or eliminate refractive error, myopic children undergoing OrthoK have shown significant slowing of axial elongation and myopic progression. This review presents data on the efficacy, benefits, and risks of the use of OrthoK to slow axial elongation in myopic children. It also discusses how OrthoK fits into an overall strategy of myopia management in practice compared with alternative prescribed interventions to slow myopic progression. Other factors discussed are patient candidacy, impact on vision-related quality of life, and use of OrthoK in combination with pharmaceutical agents. With precise fitting, careful follow-up, and patient compliance with recommended lens cleaning and disinfection, OrthoK is a safe and effective method to slow axial elongation in children.

show abstract

One‐year results of the Variation of Orthokeratology Lens Treatment Zone (VOLTZ) Study: a prospective randomised clinical trial

Cited by 55 publications

References 46 publications

The Effect of Lens Design on Corneal Power Distribution in Orthokeratology

The Effect of Lens Design on Corneal Power Distribution in Orthokeratology

Factors associated with faster axial elongation after orthokeratology treatment

The Role of Orthokeratology in Myopia Management

Contact Info

Product

Resources

About