One-Year Results of Prospective Research Study Using 10 kHz Spinal Cord Stimulation in Persistent Nonoperated Low Back Pain of Neuropathic Origin: Maiden Back Study

Systematic Literature Review of Spinal Cord Stimulation in Patients With Chronic Back Pain Without Prior Spine Surgery

“…The full texts of 109 articles were subsequently screened for eligibility, and 16 were included in this review, representing 10 primary studies and 6 secondary publications. [35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50] Reasons for exclusion of articles during abstract screening and full-text screening included not meeting the criteria for patient populations, study designs, follow-up periods, or interventions (ie, not SCS), irretrievable full texts, nonclinical studies, and conference presentations.…”

The Role of Spinal Cord Stimulation in Reducing Opioid Use in the Setting of Chronic Neuropathic Pain

“…Fourteen of the 17 studies provided data on the percentage of participants who had reduced their opioid dose from preimplantation levels at 12 months postimplantation. 9,[15][16][17][18][19]21,[23][24][25][26][27][28][29] These percentages ranged from 30% to 89%, with 12 studies demonstrating reduction in opioid use in 40% to 72% of participants. 9,[15][16][17][18][19][20][21]23,24,27,28 Mean or median opioid use decreases ranged from 4.1 morphine milligram equivalents (MME) to 120 MME, with 11 studies reporting decreases from 18.91 MME to 57 MME, 9,14,18,[20][21][22][23][24][25][26]28 and 9 studies reporting decreases from 18.92 MME to 30.6 MME.…”

“…9,[15][16][17][18][19]21,[23][24][25][26][27][28][29] These percentages ranged from 30% to 89%, with 12 studies demonstrating reduction in opioid use in 40% to 72% of participants. 9,[15][16][17][18][19][20][21]23,24,27,28 Mean or median opioid use decreases ranged from 4.1 morphine milligram equivalents (MME) to 120 MME, with 11 studies reporting decreases from 18.91 MME to 57 MME, 9,14,18,[20][21][22][23][24][25][26]28 and 9 studies reporting decreases from 18.92 MME to 30.6 MME. 9,14,18,[20][21][22][24][25][26] There were 4 studies that provided data on the preimplantation opioid dose that significantly increased likelihood of opioid use discontinuation at 12 months postimplantation.…”

French guidelines for neuropathic pain: An update and commentary

“…Another neuromodulation technique of major interest for some refractory neuropahtic pain conditions is spinal cord stimulation. Newer stimulation paradigms using very high frequency (10 KHz) now appear highly effective and have the advantage of being free of paresthesia [29][30][31]. Regarding the potential relevance of a screening trial before permanent implantation, a recent study showed that although it may have diagnostic utility, there was no evidence that a screening trial strategy provided superior patient outcomes or was cost-effective compared to a no trial screening approach [32].…”