One-Year Results of Health-Related Quality of Life Among Patients Undergoing Transcatheter Aortic Valve Implantation

Krane, Markus; Deutsch, Marcus-André; Piazza, Nicolò; Muhtarova, Teodora; Elhmidi, Yacine; Mazzitelli, Domenico; Voß, Bernhard; Ruge, Hendrik; Badiu, Catalin Constantin; Kornek, Matthias; Bleiziffer, Sabine; Lange, Rüdiger

doi:10.1016/j.amjcard.2012.02.021

Cited by 35 publications

(24 citation statements)

References 18 publications

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“…These factors may lead individuals to withdraw from activities and previous social contacts losing their social relations and social support over a longer period of time preoperatively when cardiac-related symptoms arebecoming more and more apparent. Postprocedurely, it might take longer to reverse the decay of social activities and relationships represented in the SF-36 domains social functioning and role emotional [47, 48]. …”

Section: Summary Of Hrqol and Functional Outcomes In Patients Undergomentioning

confidence: 99%

“…Likewise, in accordance with Fairbairne et al ., female gender was also associated with less HrQoL improvements at 3 months However, the difference failed to reach statistical significance at 12 months. Notably, no association could be found for STS- or logEuroScore, other hemodynamic parameters or comorbidities [48]. …”

Section: Patient- and Procedure-related Factors Predictive For Qualitmentioning

confidence: 99%

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Beyond Adding Years to Life: Health-related Quality-of-life and Functional Outcomes in Patients with Severe Aortic Valve Stenosis at High Surgical Risk Undergoing Transcatheter Aortic Valve Replacement

Deutsch¹,

Bleiziffer²,

Elhmidi³

et al. 2014

CCR

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Aortic valve stenosis (AVS) is the most frequent acquired valvular heart disease in western industrialized countries and its prevalence considerably increases with age. Once becoming symptomatic severe AVS has a very poor prognosis. Progressive and rapid symptom deterioration leads to an impairment of functional status and compromised healthrelated quality-of-life (HrQoL) simultaneously. Until recently, surgical aortic valve replacement (SAVR) has been the only effective treatment option for improving symptoms and prolonging survival. Transcatheter aortic valve replacement (TAVR) emerged as an alternative treatment modality for those patients with severe symptomatic AVS in whom the risk for SAVR is considered prohibitive or too high. TAVR has gained clinical acceptance with almost startling rapidity and has even quickly become the standard of care for the treatment of appropriately selected individuals with inoperable AVS during recent years. Typically, patients currently referred for and treated by TAVR are elderly with a concomitant variable spectrum of multiple comorbidities, disabilities and limited life expectancy. Beyond mortality and morbidity, the assessment of HrQoL is of paramount importance not only to guide patient-centered clinical decision-making but also to judge this new treatment modality. As per current evidence, TAVR significantly improves HrQoL in high-surgical risk patients with severe AVS with sustained effects up to two years when compared with optimal medical care and demonstrates comparable benefits relative to SAVR.Along with a provision of a detailed overview of the current literature regarding functional and HrQoL outcomes in patients undergoing TAVR, this review article addresses specific considerations of the HrQoL aspect in the elderly patient and finally outlines the implications of HrQoL outcomes for medico-economic deliberations.

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Section: Summary Of Hrqol and Functional Outcomes In Patients Undergomentioning

confidence: 99%

Section: Patient- and Procedure-related Factors Predictive For Qualitmentioning

confidence: 99%

Beyond Adding Years to Life: Health-related Quality-of-life and Functional Outcomes in Patients with Severe Aortic Valve Stenosis at High Surgical Risk Undergoing Transcatheter Aortic Valve Replacement

Deutsch¹,

Bleiziffer²,

Elhmidi³

et al. 2014

CCR

Self Cite

View full text Add to dashboard Cite

show abstract

“…Most of our patients were living at home, which supports the above reports. Whether TAVI potentially offers superior quality of life for these patients remains to be determined, but significant improvement in functional status have been reported with catheter-based aortic therapy in very high [27], high [28], and moderate [29] risk patients.…”

Section: Commentmentioning

confidence: 96%

Aortic Valve Replacement in Octogenarians With Prior Cardiac Surgery

Timek

Turfe

Hooker

et al. 2015

The Annals of Thoracic Surgery

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“…Based on the European Society of Cardiology (ESC) guidelines, candidates for the TAVR procedure should gain QOL improvement and a life expectancy of more than 1 year post‐TAVR procedure (O'Sullivan, Stortecky, Buellesfeld, Wenaweser, & Windecker, ). When the QOL of a patient with severe symptomatic AS improves 1 or 2 years post‐TAVR, that is an important indicator of the effectiveness of the TAVR (Krane et al., ; Leon et al., ; Makker et al., ; Reynolds et al., 2012; Smith et al., ).…”

Section: The Pros and Cons Of Tavrmentioning

confidence: 99%

“…Krane et al. () used the SF‐36 questionnaire three times with 186 patients undergoing TAVR: on the day prior to procedure, 3 months after the procedure, and 12 months post‐TAVR. A total of 106 patients completed the survey for 1 year and reported improvement in QOL and physical functioning more than social and mental health (Krane et al., 2012).…”

Section: The Pros and Cons Of Tavrmentioning

confidence: 99%

Is transcatheter aortic valve replacement a safe treatment for elderly patients with severe aortic valve stenosis?

Mohammadi

Hill

Chaney

2016

Journal of the American Association of Nurse Practitioners

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Purpose This article's purpose is to make advanced practice nurses (APNs) aware of a minimally invasive transcatheter aortic valve replacement (TAVR) for treating symptomatic severe aortic valve stenosis in elderly patients. These patients are not safe surgical candidates because of their age and prohibitive risk profile, but they can benefit from valve replacement. Methods A systematic literature review was completed by searching online databases such as CINAHL, PubMed, and Google. Research articles from 2008 to 2014 were retrieved from various medical journals such as The American Journal of Cardiology, Yale Journal of Biology and Medicine, Journal of the American Medical Association, and New England Journal of Medicine. Key words used in the search were aortic valve replacement, elderly patients, and severe aortic stenosis (AS). Conclusion Minimally invasive TAVR is highly superior to the medical treatment including aortic valvuloplasty and is noninferior to the surgical aortic valve replacement for the treatment of symptomatic severe aortic valve stenosis in elderly patients who are not safe surgical candidates. Implications for practice APNs have the education and skills to diagnose AS. Hence, they should stay abreast of new treatments and provide safe care and referrals for their patients diagnosed with severe AS.

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One-Year Results of Health-Related Quality of Life Among Patients Undergoing Transcatheter Aortic Valve Implantation

Cited by 35 publications

References 18 publications

Beyond Adding Years to Life: Health-related Quality-of-life and Functional Outcomes in Patients with Severe Aortic Valve Stenosis at High Surgical Risk Undergoing Transcatheter Aortic Valve Replacement

Beyond Adding Years to Life: Health-related Quality-of-life and Functional Outcomes in Patients with Severe Aortic Valve Stenosis at High Surgical Risk Undergoing Transcatheter Aortic Valve Replacement

Aortic Valve Replacement in Octogenarians With Prior Cardiac Surgery

Is transcatheter aortic valve replacement a safe treatment for elderly patients with severe aortic valve stenosis?

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