One-Year Prospective Health-Related Quality-Of-Life Outcomes in Patients Treated with Conservative Method, Endovascular Treatment or Open Surgery for Symptomatic Lower Limb Atherosclerotic Disease

Abstract

Deterioration of any clinical characteristics or HRQoL was not observed after any of the treatment modalities. Surgery gave LLAD patients a good clinical outcome and HRQoL for at least a year, whereas patients who were treated with endovascular and especially conservative treatment gained limited benefits.

Assessment of functional status and quality of life in claudication

“…Additionally, lower extremity bypass surgery also improved pain, physical mobility and sleep 1 year after the intervention. 47 However, recently it was found that quality of life returned to pre-surgery levels in the domains of pain and physical mobility at 1 year follow-up. 48 These findings suggest that, although endovascular therapy improves HRQOL acutely, long-term outcomes may not be as durable.…”

“…Other studies have yielded mixed results when examining the change in HRQOL following vascular intervention for IC. 47–55 Koivunen and Lukkarinen 47 determined that revascularization improved the domains of emotional reactions, energy and social isolation. Additionally, lower extremity bypass surgery also improved pain, physical mobility and sleep 1 year after the intervention.…”

2016 AHA/ACC Guideline on the Management of Patients with Lower Extremity Peripheral Artery Disease: Executive Summary

“…COR LOE RECOMMENDATIONS I A When surgical revascularization is performed, bypass to the popliteal artery with autogenous vein is recommended in preference to prosthetic graft material (226)(227)(228)(229)(230)(231)(232)(233)(234). IIa B-NR Surgical procedures are reasonable as a revascularization option for patients with lifestyle-limiting claudication with inadequate response to GDMT, acceptable perioperative risk, and technical factors suggesting advantages over endovascular procedures (190,230,(235)(236)(237). III: Harm B-R Femoral-tibial artery bypasses with prosthetic graft material should not be used for the treatment of claudication (238)(239)(240).…”

Concept of Major Life-Changing Decisions in Life Course Research

“…However, long-term treatment may have its own disadvantages, which may cause further adverse impacts on patients' QoL. There have been advances in pharmacological as well as surgical treatments and attempts have been made to assess the long-term impact of these new approaches on patients' lives [48][49][50][51][52][53][54][55][56][57][58].…”