One-year clinical and parasitological follow-up of dogs treated with marbofloxacin for canine leishmaniosis

Rougier, Sandrine; Hasseine, Lilia; Delaunay, Pascal; Michel, Grégory; Marty, Pierre

doi:10.1016/j.vetpar.2011.11.016

Cited by 25 publications

(26 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…If after 2–3 months the electrophoretograms still show abnormal profiles, the possible presence of concurrent diseases such as other vector‐borne infections should be considered, especially if the gammopathy tends to be characterized by narrower peaks (Figure ). Treatments with miltefosine or with other drugs may require more time to be beneficial (more than 2 months to observe a decrease in γ‐globulins) and are also characterized by more frequent relapses after transient normalization of laboratory profiles …”

Section: Future Perspectivesmentioning

confidence: 99%

“…Treatments with miltefosine or with other drugs may require more time to be beneficial (more than 2 months to observe a decrease in cglobulins) and are also characterized by more frequent relapses after transient normalization of laboratory profiles. 206,207 Compared with serum protein electrophoresis, monitoring the concentration of APPs provides earlier information regarding the success of treatments with antimonials. C-reactive protein and SAA start to decrease within 2 weeks after treatment and may return to within the RI in about one month.…”

Section: Monitoring the Clinical Statusmentioning

confidence: 99%

See 1 more Smart Citation

Laboratory tests for diagnosing and monitoring canine leishmaniasis

Paltrinieri

Gradoni

Roura

et al. 2016

Veterinary Clinical Pathol

141

232

View full text Add to dashboard Cite

Although several reviews on canine leishmaniasis have been published, none thoroughly described clinicopathologic abnormalities and their clinical usefulness. The aim of this review was to provide information concerning current diagnostic tests relevant for clinical pathologists and from a practical perspective. Specifically, in canine leishmaniasis, nonregenerative normocytic normochromic anemia, thrombocytopenia, or leukogram changes may be present. Clinical chemistry and urinalysis may indicate renal dysfunction (azotemia, decreased urine specific gravity, proteinuria) and an inflammatory/immune response (increased acute phase proteins [APP] or α - and/or γ-globulins). Although a potential gammopathy is usually polyclonal, it may also appear oligo- or monoclonal, especially in dogs coinfected by other vector-borne pathogens. When lesions are accessible to fine-needle aspiration (lymphoadenomegaly, nodular lesions, joint swelling), cytology is strongly advised, as the presence of Leishmania amastigotes in a pattern of pyogranulomatous inflammation or lymphoplasmacytic hyperplasia is diagnostic. If the cytologic pattern is inconclusive, the parasite should be identified by histology/immunohistochemistry or PCR on surgical biopsies. Alternatively, cytology and PCR may be performed on bone marrow samples where amastigotes, along with erythroid hypoplasia, myeloid hyperplasia, plasmacytosis, or secondary dysmyelopoiesis can be observed. Dogs with overt leishmaniasis generally have high antibody titers, while low titers predominate in immunologically resistant infected dogs or in exposed dogs with no parasite confirmation. Quantitative serology is recommended in clinically suspect dogs as high-titer antibodies titers may confirm the clinical diagnosis. In confirmed and treated dogs, renal function and inflammatory/immune response variables should be periodically monitored.

show abstract

Section: Future Perspectivesmentioning

confidence: 99%

Section: Monitoring the Clinical Statusmentioning

confidence: 99%

Laboratory tests for diagnosing and monitoring canine leishmaniasis

Paltrinieri

Gradoni

Roura

et al. 2016

Veterinary Clinical Pathol

141

232

View full text Add to dashboard Cite

show abstract

“…17 It is similar to the Vizsla phenotype of idiopathic seba- Table 1. Frequency of the different types of cutaneous lesions in dogs with leishmaniosis due to Leishmania infantum overall and in dogs with leishmaniosis and skin lesions 6,7,9,10,12,17,18,24,39,41,50,90,[102][103][104][105][106][107][108][109][110][111][112][113] ceous adenitis; 12,15,24,25 however, in CanL sebaceous adenitis is regularly accompanied by additional findings that are not present in idiopathic sebaceous adenitis (granulomatous to pyogranulomatous nodular dermatitis in the interfollicular dermis), and follicular keratosis is milder and usually not accompanied by a dilated follicular infundibulum. 25 The parasite density in the lesional skin of dogs with exfoliative dermatitis is mild to moderate, and using immunohistochemistry, amastigotes were visualized in 31% of biopsies.…”

Section: Introductionmentioning

confidence: 99%

Cutaneous involvement in canine leishmaniosis due to Leishmania infantum (syn. L.chagasi)

Saridomichelakis

Koutinas

2014

Veterinary Dermatology

View full text Add to dashboard Cite

show abstract

“…Considerando o nosso modelo e as simplificações dadas pelas Eq. (99) a (110) (os termos do tipo a k , 1 ≤ k ≤ 6, podem ser verificados no Apêndice), nós obtemos (os detalhes dos cálculos foram suprimidos):…”

Section: Cães Que Seriam Vacinadosunclassified

Modelo de otimização para o controle da leishmaniose: análise epidemiológica e econômica

Shimozako¹

View full text Add to dashboard Cite

Abreviaturas dos títulos dos periódicos de acordo com List of Journals Indexed in Index Medicus. Observação: esta tese foi corrigida em 5 de fevereiro de 2016. Entretanto, apenas pequenos erros ortográficos e de conceituação na revisão de literatura foram modificados. Todo o conteúdo referenteà metodologia, aos resultados,à discussão eà conclusão foram mantidos. CONCLUSÕES 132 REFERÊNCIAS 134 Apêndice Shimozako HJ Modelo de otimização para o controle da leishmaniose Faculdade de Medicina 12 Universidade de São Paulo LISTA DE FIGURAS Evolução no número de casos e deóbitos no período de 2001 a 2013.. .. 19 2Áreas de maior concentração de casos de leishmaniose visceral.Brasil, 2006 e 2007.

show abstract

One-year clinical and parasitological follow-up of dogs treated with marbofloxacin for canine leishmaniosis

Cited by 25 publications

References 36 publications

Laboratory tests for diagnosing and monitoring canine leishmaniasis

Laboratory tests for diagnosing and monitoring canine leishmaniasis

Cutaneous involvement in canine leishmaniosis due to Leishmania infantum (syn. L.chagasi)

Modelo de otimização para o controle da leishmaniose: análise epidemiológica e econômica

Contact Info

Product

Resources

About