One-stop assessment of renal function and renal artery in hypertensive patients with suspected renal dysfunction: non-enhanced MRI using spatial labeling with multiple inversion pulses

Liang, Ping; Xu, Chuou; Tripathi, Pratik; Li, Jiali; Li, Anqin; Hu, Daoyu; Kamel, Ihab R.; Li, Zhen

doi:10.1007/s00330-020-07088-x

Cited by 5 publications

(1 citation statement)

References 30 publications

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“…A previous study found that SLEEK could display the renal artery by preparing multiple space selective inversion recovery pulses to label the blood flow in a more flexible way (13). Further, the optimal blood suppression inversion time in SLEEK was found to improve the corticomedullary contrast ratio of patients with renal insufficiency and healthy volunteers, enabling accurate measurement of renal cortical thickness to further assess renal function without contrast agents (14)(15)(16).…”

Section: Introductionmentioning

confidence: 99%

Assessment of renal function using magnetic resonance quantitative histogram analysis based on spatial labeling with multiple inversion pulses

Liang¹,

Li²,

Xu³

et al. 2021

Ann Transl Med

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Background: The incidence of chronic kidney disease (CKD) is high, and is easy to develop into endstage renal disease (ESRD), which requires kidney dialysis or kidney transplantation. Therefore, we want to explore the clinical value of magnetic resonance quantitative histogram analysis based on spatial labeling with multiple inversion pulses (SLEEK) in assessing renal function in the early stage. Methods: One hundred and twenty-nine patients underwent abdominal MRI examination, including a coronal SLEEK sequence. The patients were divided into the control group [CG, 47 cases, estimated glomerular filtration rate (eGFR) >90], the mild renal function impairment (mRI) group (48 cases, eGFR =60-90), and the moderate to severe renal function impairment (m-sRI) group (34 cases, eGFR <60). Two experienced radiologists delineated cortex and medulla regions of interest (ROIs) on SLEEK images to obtain cortex and medulla quantitative histogram parameters [Mean, Median, Percentiles (5 th , 10 th , 25 th , 75 th , and 90 th ), Skewness, Kurtosis, and Entropy] using FireVoxel. These histogram parameters were compared by proper statistical methods such as one-way analysis of variance, the χ 2 test, and receiver operating characteristic (ROC) curve analysis. Results: Four histogram parameters (Inhomogeneity cortex , Skewness cortex , Kurtosis medulla , and Entropy medulla ) differed significantly between the CG and the mRI group. One medulla (Entropy medulla ) and nine cortex (Mean cortex , Median cortex , Kurtosis cortex , Entropy cortex , and 5 th , 10 th , 25 th , 75 th , and 90 th Percentile cortex ) histogram parameters were significantly different between the m-RI and m-sRI groups. The most relevant parameter to eGFR was Inhomogenity cortex (r=−0.450, P<0.001). Inhomogeneity cortex had the largest area under the curve (AUC) for differentiating the mRI group from the CG (AUC =0.718, 95% CI, 0.616-0.806), while 25 th Percentile cortex generated the largest AUC (AUC =0.786, 95% CI, 0.681-0.869) for differentiating the mRI and m-sRI groups. Conclusions: Quantitative histogram parameters based on a SLEEK sequence can be used to supplement renal dysfunction assessment. Cortex histogram parameters are more valuable for evaluating renal function than medulla histogram parameters.

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Section: Introductionmentioning

confidence: 99%

Assessment of renal function using magnetic resonance quantitative histogram analysis based on spatial labeling with multiple inversion pulses

Liang¹,

Li²,

Xu³

et al. 2021

Ann Transl Med

Self Cite

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The added value of superb microvascular imaging for renal cortical thickness measurement in chronic kidney disease

Limpisook,

Waongenngarm,

Siripongsakun

et al. 2024

J of Clinical Ultrasound

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PurposeThe aim of this study was to evaluate renal parenchymal thickness and renal cortical thickness measurements on brightness mode ultrasound (B‐mode US) and B‐mode US + Superb Microvascular Imaging (SMI) technique, comparing with computed tomography (CT) or magnetic resonance imaging (MRI) serving as a reference standard.MethodsRenal parenchymal thickness and renal cortical thickness measurements were obtained from B‐mode US, B‐mode US + SMI, and CT/MRI in a group of healthy subjects and a group of patients with chronic kidney disease (CKD). The mean differences and correlations of renal parenchymal thickness and renal cortical thickness were analyzed using dependent pair t‐test and Pearson's correlation, respectively.ResultsThe mean difference in renal cortical thickness measurements between B‐mode US + SMI and CT/MRI was lower than the mean difference between B‐mode US alone and CT/MRI. Additionally, renal cortical thickness measured using B‐mode US + SMI showed a stronger correlation with values obtained from CT/MRI than values measured using standard B‐mode US alone.ConclusionThe measurement of renal cortical thickness by B‐mode US + SMI is more accurate than that by B‐mode US alone.

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Non-contrast-enhanced MR angiography of left gastric vein in patients with gastroesophageal varices: morphology and blood supply analysis

Zou,

Liu,

Tan

et al. 2023

Eur Radiol

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One-stop assessment of renal function and renal artery in hypertensive patients with suspected renal dysfunction: non-enhanced MRI using spatial labeling with multiple inversion pulses

Cited by 5 publications

References 30 publications

Assessment of renal function using magnetic resonance quantitative histogram analysis based on spatial labeling with multiple inversion pulses

Assessment of renal function using magnetic resonance quantitative histogram analysis based on spatial labeling with multiple inversion pulses

The added value of superb microvascular imaging for renal cortical thickness measurement in chronic kidney disease

Non-contrast-enhanced MR angiography of left gastric vein in patients with gastroesophageal varices: morphology and blood supply analysis

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