One-step hydrothermal approach to fabricate carbon dots from apple juice for imaging of mycobacterium and fungal cells

Mehta, Vaibhavkumar N.; Jha, Sanjay Kumar; Basu, Hirakendu; Singhal, R. K.; Kailasa, Suresh Kumar

doi:10.1016/j.snb.2015.02.104

Cited by 410 publications

(162 citation statements)

References 55 publications

Supporting

Mentioning

151

Contrasting

Unclassified

Order By: Relevance

“…They have great promise for a variety of practical applications, such as bio-chemical assays, photocatalysis and cell imaging 11, 15, 16 . Particularly, heteroatoms (N or S or B) doped CNDs 17, 18 were paid considerable attention since they not only maintain most advantages of blank CNDs, but also efficiently improve their properties such as avoiding their self-quenching and improving the PL quantum yield 19 .…”

Section: Introductionmentioning

confidence: 99%

Enhanced-quantum yield sulfur/nitrogen co-doped fluorescent carbon nanodots produced from biomass Enteromorpha prolifera: synthesis, posttreatment, applications and mechanism study

Liu

et al. 2017

Sci Rep

View full text Add to dashboard Cite

Enteromorpha prolifera (E. prolifera), one of the main algae genera for green tide, significantly influences both the coastal ecological environment and seawater quality. How to effectively utilize this waste as reproducible raw resource with credible application mechanism are urgent environmental issues to be solved. Herein, E. prolifera was converted to attractive fluorescent carbon nanodots (CNDs) by one-pot green hydrothermal process. The purity and quantum yields for the as-prepared CNDs can be enhanced upon the post-treatment of ethanol sedimentation. The CNDs can be well dispersed in aqueous medium with uniform spherical morphology, narrow size distribution and average size of 2.75 ± 0.12 nm. The ease synthesis and relatively high quantum yields of the CNDs make E. prolifera inexpensive benefit to the human and nature, such as applications in efficient cell imaging and fiber staining. Furthermore, it was discovered that the fluorescence intensity of the CNDs can be selectively quenched upon Fe3+ addition, which can be used for specific sensitive assay and removal of Fe3+ in aqueous medium. More importantly, it was reasonably proposed that the quenching was resulted from the synergistic effects of CNDs aggregation and Fe3+-CNDs charge-transfer transitions due to the coordination interactions between Fe3+ and the oxygenous groups on the CNDs.

show abstract

Section: Introductionmentioning

confidence: 99%

Enhanced-quantum yield sulfur/nitrogen co-doped fluorescent carbon nanodots produced from biomass Enteromorpha prolifera: synthesis, posttreatment, applications and mechanism study

Liu

et al. 2017

Sci Rep

View full text Add to dashboard Cite

show abstract

“…Usually, the upconvertion photoluminescence was ascribed to the multi photon active process similar to the previously reported studies . The fluorescence quantum yield of the GSC‐dots was calculated to be about 9.27%, which is higher than the previous reported study . The pH dependent feature of the GSC‐dots (0.02 g mL −1 ) was studied at different pH which revealed that fluorescence (FL) intensity was barely changed in the region of pH value 5–9 at 360 nm excitation wavelength (Figure d).…”

Section: Resultsmentioning

confidence: 99%

One‐Step Synthesis of Fluorescent Carbon Dots for Bio‐Labeling Assay

Das

Bose

Das

et al. 2018

Macromolecular Symposia

View full text Add to dashboard Cite

Luminescent carbon dots, a newcomer in the domain of nanolights and nanomaterials have been studied extensively since past few years due to their fascinating properties of sensor design, biocompatibility, cell tracking, or fluorescence based live cell assays, medical diagnosis, photocatalysts, and also being potential building blocks for nanodevices. In this study, one‐pot green synthesis of water dispersible fluorescent carbon dots have been synthesized by using roasted gram shells. The structural and optical properties of the as‐prepared carbon dots are characterized by TEM, FTIR, UV‐vis absorption, photoluminescence spectra. The carbon dots showed greenish blue fluorescence under UV irradiation, excitation dependent emission, upconverted emission, high pH tolerance, and good biocompatibility. The carbon dots labeled Escherichia coli (E. coli) unveiled multicolor emission behavior under different excitation wavelength. These carbon dots showed their superiority with respect to commercially available synthetic dyes which have severe limitations including photobleaching effect, high cost, etc. The incorporation of carbon dots in the bacterial culture medium does not show any kind of growth delay of the bacterium up to 400 mg mL−1. The goal is to establish this carbon dots in bio‐labeling assay with its physicochemical features (small particle size, high luminescence efficiency, good biocompatibility, low toxicity) against various environments such as wide range of pH, high ionic medium. Concisely, this work bestows an innovative aspect to the commercialization of carbon dots as a potent alternative to synthetic organic dyes for multicolor emitting probes for cell‐labeling gram negative bacteria E. coli.

show abstract

“…99.3 nm, which is approximately the same as that for the most reported carbon dots. [16][17][18] The mean lifetime of CDs was found to be 7.4 ns (Fig. S5, ESI ‡), showing that the decay of fluorescence emission was non-monoexponential and the possible mechanism of fluorescence might be attributed to the radiative recombination of the energy-trapping sites on the CDs.…”

Section: Characterization Of Cdsmentioning

confidence: 98%

“…15 Due to their ultra-small size and biocompatibility, CDs have been used as fluorescent probes for imaging bacterial and cancer cells. [16][17][18][19] As a result, a few reports have described the use of CDs as carriers for the delivery of anticancer drugs. Briefly, Zhou's group illustrated the use of negatively charged CDs as caps on positively charged mesoporous silica NPs for delivering doxorubicin.…”

Section: Introductionmentioning

confidence: 99%

Fluorescent carbon dots derived from vancomycin for flutamide drug delivery and cell imaging

et al. 2016

Self Cite

View full text Add to dashboard Cite

In this work, fluorescent carbon dots were prepared using vancomycin as a precursor via hydrothermal treatment. The synthesized fluorescent CDs are well dispersed in water and exhibited a quantum yield of 6.47%. The functionalization of an anticancer drug flutamide on the surfaces of CDs endowed them with the ability to act as good candidates for capturing and releasing the flutamide drug in an acidic microenvironment (pH 5.2). The flutamide-loaded CDs were found to be biocompatible towards MCF-7 (human breast cancer) and SH-SY5Y (human neuroblastoma) cells with the survival rate of 75%. The carbon dots and flutamide-loaded carbon dots were used as fluorescent probes for the imaging of cells and showed good target specific action. The carbon dots showed negligible toxicity to MCF-7 cells. The application of flutamide-coated carbon dots for anticancer drug delivery has also been demonstrated. Therefore, we have evaluated flutamide-loaded carbon dot hybrids as prospective candidates to achieve simultaneous imaging and drug delivery in cancer cells.

show abstract

One-step hydrothermal approach to fabricate carbon dots from apple juice for imaging of mycobacterium and fungal cells

Cited by 410 publications

References 55 publications

Enhanced-quantum yield sulfur/nitrogen co-doped fluorescent carbon nanodots produced from biomass Enteromorpha prolifera: synthesis, posttreatment, applications and mechanism study

Enhanced-quantum yield sulfur/nitrogen co-doped fluorescent carbon nanodots produced from biomass Enteromorpha prolifera: synthesis, posttreatment, applications and mechanism study

One‐Step Synthesis of Fluorescent Carbon Dots for Bio‐Labeling Assay

Fluorescent carbon dots derived from vancomycin for flutamide drug delivery and cell imaging

Contact Info

Product

Resources

About