One step facile synthesis, characterization and antimicrobial properties of Mg-doped CuO nanostructures

Revisiting Mg solubility in CuO nanorods: limit probed by neutron diffraction and effect on the particle toxicity towards bacteria in water

“…No conclusion on the role played by the released cupric ions in the activity can therefore be drawn, in contrast to what these authors say. 9 Furthermore, in Din et al 8 and Lv et al 9 studies, no clear evidence of successful Mg and Zn substitutions is given since impurity is present for some samples (additional Bragg peaks in the range 35° ≤ 2 θ ≤ 45° 8 ) and no linear evolution of the unit cell parameters with the substitute content (Vegard's law 10 ) is shown. While only the bactericidal activity of Cu 0.88 Zn 0.12 O 11 has been evaluated, it remains completely unknown for any Mg-substituted CuO.…”

“…Concerning the use of CuO nanoparticles as a disinfectant, the performances reported by Applerot et al 4 do not meet the European performance standards of hospital/healthcare disinfection (EN 1040) which require to kill more than 99.999% of bacteria (5 Log 10 reduction) at low concentrations. In this context, partial substitutions of cupric ions in CuO by Mg 2+ or Zn 2+ have also been tested up to 15 mol% by Din et al 8 and Lv et al 9 Growth inhibition of these bacteria is noted only after 24 h in a 0.05 mg mL −1 suspension of Cu 0.95 Mg 0.05 O or Cu 0.97 Zn 0.03 O nanoparticles in nutrient media. 9 A significant release of cupric ions from these particles is reported by these authors in a Tris buffer solution, which is not the medium they used to determine bacteriostatic activity.…”

Structural, Optical, and Antibacterial Efficacy of Pure and Zinc-Doped Copper Oxide Against Pathogenic Bacteria

“…The synthesis of a Zinc (Zn)-doped Copper oxide nanostructure (Zn-doped CuO-NS) and its chemical and physical properties, including its crystal structure and magnetization, has been explored as a function of temperature [ 33 ]. Similarly, it was found that doping of magnesium in CuO-NSs possesses anti-cancer and antimicrobial activity for various microbial strains [ 34 ]. There have also been reports on the antimicrobial activity of Zn-doped CuO-coated fabrics experienced against E. coli , S. aureus , and multidrug-resistant bacteria [ 24 ].…”

Morphological Control of Nanoporous Copper Formed from Conversion Reaction Synthesis

“…Mg-doped copper oxide was synthesized in two steps . In a first step, CuSO 4 ·5H 2 O and Mg­(NO 3 ) 2 (20:1 molar excess) were dissolved in water.…”

“…Mg-doped copper oxide was synthesized in two steps. 19 In a first step, CuSO 4 •5H 2 O and Mg(NO 3 ) 2 (20:1 molar excess) were dissolved in water. Second, the precursor solution was mixed (dropwise) with a NaOH solution at 80 °C for 2 h under continuous stirring, resulting in the immediate formation of a black precipitate.…”