One-step enzymatic synthesis of poly(p-dioxanone-co-butylene-co-succinate) copolyesters with well-defined structure and enhanced degradability

Abstract

One-step enzymatic synthesis of poly(p-dioxanone-co-butylene-co-succinate) copolyesters with well-defined structure and enhanced degradability

Recent advances in the synthesis of biodegradable polyesters by sustainable polymerization: lipase-catalyzed polymerization

“…90 Aerward, a series of monomers have been utilized in this tandem enzymatic polymerization (Fig. 6), e.g., diethyl succinate, 1,4-butanediol and p-dioxanone, 91 L-lactide (LLA) with diesters and diols, 92 u-pentadecalactone (PDL) with diethyl carbonate (DEC), and 1,4-butanediol, 93 lactone with disuldecontaining diester and diol. 94 Among this synthesized polyester, a new biodegradable terpolymerization poly(amine-coesters) formed synthesized by Jiang et al through combined ring-opening and condensation copolymerization of the lactone with dialkyl diester and amino-substituted diols monomers particularly noteworthy.…”

Poly(ether ester) and related block copolymers via organocatalytic ring‐opening polymerization

“…Benefiting from the coexistence of ester and ether bonds in the repeating units, poly( p ‐dioxanone) (PPDO) produced by ring‐opening polymerization (ROP) of p ‐dioxanone (PDO) has attracted much attention in the fields of bioengineering and environmental materials 1–5 . Compared to the conventional aliphatic polyesters that comprise sole ester units, PPDO displays a glass transition temperature ( T g ) of −10 °C and a melting point ( T m ) at 110 °C and shows superior performances (hydrophilicity, degradability and flexibility) 6–8 . For example, PPDO can completely degrade in human body within a period of 180 days that is similar to polyglycolide (PGA) but quite faster than polylactide (PLA), thus render PPDO satisfactory for many biomedical applications 9,10 .…”

Organobase/urea catalyzed ring opening polymerization of 3‐methyl‐1, 4‐dioxan‐2‐one to prepare chemically recyclable poly(ether ester)

“…Its polymerization efficiency was strongly dependent on the purity of the monomer and the activity of the catalysts. [33][34][35] Interestingly, PpDO showed the thermal induced depolymerization to monomer with a yield of more than 90%. 31 3-Methyl-1, 4-dioxan-2-one (MDO) is a homologue of PDO.…”

“…Their results showed that the ROP of pDO needs relatively challenging conditions. Its polymerization efficiency was strongly dependent on the purity of the monomer and the activity of the catalysts 33–35 . Interestingly, PpDO showed the thermal induced depolymerization to monomer with a yield of more than 90% 31 .…”