One-step electrochemical fabrication of a nickel oxide nanoparticle/polyaniline nanowire/graphene oxide hybrid on a glassy carbon electrode for use as a non-enzymatic glucose biosensor

Abstract

We propose here a novel non-enzymatic glucose biosensor based on nickel oxide nanoparticles/polyaniline 10 nanowire/graphene oxide modified glassy carbon electrode (NiONPs/PANiNW/GO/GCE). The composite, prepared by mixing aniline with graphene oxide (GO) together, was transferred to the surface of bare glassy carbon electrode (GCE). The modified electrode was then immersed into deoxygenated 50 mM NiCl2 solution and electrodeposited at -0.8V for 400s to obtain NiONPs/PANiNW/GO/GCE. We characterized the morphology and electrochemical performance of the modified electrode using scanning electron microscopy (SEM) and cyclic voltammetry (CV), respectively. We found that 15NiONPs/PANiNW/GO/GCE exhibited higher electrocatalytic activity to glucose oxidation than nickel oxide nanosheets/graphene oxide modified glassy carbon electrode (NiONS/GO/GCE) in alkaline solution. The sensitivity of the sensor towards glucose oxidation was 376.22 μA mM −1 cm −2 with a linearity range of 2 μM -5.560 mM and a detection limit of 0.5 μM (S/N = 3). The sensor selectively detected glucose in presence of the common interfering species such as ascorbic acid, uric acid, and dopamine. Furthermore, we examined the applicability of this modified electrode as a sensing 20 probe for the detection of the glucose concentrations in the fetal bovine serum. We conclude that the highly selective and sensitive NiONPs/PANiNW/GO/GCE based non-enzymatic glucose sensor has potential to be applied for accurate measurement of glucose level for various practical purposes such as clinical diagnosis, food analysis, etc.

Electrochemical fabrication and evaluation of a self-standing carbon nanotube/carbon fiber composite electrode for lithium-ion batteries

“…A facile and simple EPD technique was adopted to develop a self-standing CNT/CF composite anode. Since development of several composites have been reported to exhibit outstanding performance for supercapacitor, [21][22][23] lithium ion battery, 24,25 and biosensor 26,27 applications; therefore, we herein attempted to enhance electrode performance of lithium ion battery using the CNT/CF composite. The electrochemical behaviors of the CNT/CF and CF anodes were evaluated using charge/discharge tests and electrochemical impedance spectroscopy (EIS) measurements.…”

Chitosan-magnetite nanocomposite as a sensing platform to bendiocarb determination

“…Among the several magnetic materials reported in the literature for analytical detection [20][21][22][23][24][25][26][27][28][29][30], iron oxides (mainly Fe 3 O 4 ) nanoparticles are the most used due to its simple preparation and superparamagnetic properties [31][32][33][34][35][36]. Iron oxide nanoparticles can be applied for simple adsorption of biomolecules [37], functionalized and/or encapsulated with polymers or silica materials for making hybrid composites, providing increased functionality [38]and biocompatibility [39].…”

Amperometric Enzyme-Free Glucose Sensor Based on Electrodeposition of Au Particles on Polyaniline Film Modified Pt Electrode

“…Conducting polymers such as polyaniline (PANI), poly(o-phenylenediamine) (PoPD), polythiophenes, poly(3, 4-ethylenedioxythiophene) (PEDOT), polyvinylferrocenium, and polypyrrole (PPY) have been researched in the fabrication of ideal sensors. [9][10][11][12][13][14][15] These polymers make available active sites for the dispersion of metal nanoparticles. The contribution of PANI is the greatest as it has a wide range of conductance (over 11 orders), excellent polymerization yield, and is stable to environmental conditions.…”