One-stage, totally laparoscopic major hepatectomy and colectomy for colorectal neoplasm with synchronous liver metastasis: Safety, feasibility and short-term outcome

Spampinato, Marcello; Mandalà, Lucio; Quarta, Giuseppe; Medico, Pietro Del; Baldazzi, Giànandrea

doi:10.1016/j.surg.2012.06.007

Cited by 43 publications

(47 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Several teams have reported the feasibility of simultaneous resection of both primary CRC and SCRLM [20][21][22][23]. However, few studies had compared patients who underwent combined resections by either open or laparoscopic approach [22,[24][25][26].…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Laparoscopic simultaneous resection of colorectal primary tumor and liver metastases: a propensity score matching analysis

et al. 2015

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 99%

“…In the literature, very few data concerning primary CRC resection and simultaneous major LLR are available [21,47]. Even in open surgery, the results of simultaneous colorectal resection and major hepatectomy are debated [12].…”

Section: Discussionmentioning

confidence: 99%

Laparoscopic simultaneous resection of colorectal primary tumor and liver metastases: a propensity score matching analysis

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Furthermore, more recently even safety and efficacy of combined resections have been reported [7][8][9][10][11], with shorter length of stay and reduced morbidity compared with staged approaches if performed in a selected population of patients [6][7][8]. Although the debate regarding the optimal timing for resection of SCLM is still open [6][7][8], mainly because of concerns regarding a presumptive higher frequency of colonic anastomosis leakage, even combined, totally laparoscopic approach for CRC and SCLM is experiencing a growing trend [21][22][23][24].…”

Section: Discussionmentioning

confidence: 99%

“…Presently, many descriptive series are available, including a still limited number of cases [24,[34][35][36][37][38], probably because an adequate experience in laparoscopic surgery of both districts is required and this factor limits widespread diffusion of this technique.…”

Section: Discussionmentioning

confidence: 99%

“…In this setting, the possibility of a totally laparoscopic approach (TLA) in combined resection of primary cancer and resectable SCLM represents an attracting option, possibly reducing complications correlated with extended laparotomy and with enhanced biological stress. Even though feasibility of TLA has been reported in the literature [21][22][23][24], no definite conclusions regarding indications and outcomes have been drawn so far.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Impact of totally laparoscopic combined management of colorectal cancer with synchronous hepatic metastases on severity of complications: a propensity-score-based analysis

et al. 2016

View full text Add to dashboard Cite

show abstract

Laparoscopic synchronous resection of colorectal cancer and liver metastases: A systematic review

Moris

Tsilimigras

Machairas

et al. 2018

Journal of Surgical Oncology

View full text Add to dashboard Cite

While colorectal and hepatic resections are commonly performed through a laparoscopic approach, the safety and feasibility of total laparoscopic synchronous resections (LSR) of colorectal liver metastasis (CRLM) have not been established. In this systematic review, short-and long-term outcomes were comparable for patientsundergoing LSR and open synchronous resection. LSR was safe and feasible for patients with synchronous CRLM and should be considered in well-selected patients. K E Y W O R D S colorectal cancer, combined resection, laparoscopy, liver metastasis, synchronous resection 1 | INTRODUCTION Colorectal cancer (CRC) is the third leading cause of cancerrelated deaths in the United States. In 2017, approximately 140 000 new cases of CRC were diagnosed with over 50 000 cancer-related deaths. 1 The liver is the most common site of metastases with 15% to 25% of patients presenting with synchronous colorectal liver metastases (CRLM) at the time of diagnosis. 2,3 Modern chemotherapy has resulted in improved response and survival rates for patients with liver metastases and has also increased the rate of resectability of CRLM in selected patients as part of a comprehensive multidisciplinary treatment strategy. In turn, resection of CRLM is now associated with 5-year survival greater than 50%. 4,5Among patients with resectable disease, surgical resection remains the only potentially curative treatment for synchronous CRLM. 4 However, the optimal operative sequence for the management of the primary tumor and metastatic liver disease remains unclear. 6 The traditional surgical strategy consists of a staged approach, in which resection of the primary tumorwith or without adjuvant chemotherapyis followed by a planned liver resection at a future date (colorectal-first approach). Alternatively, the "reverse approach" consists of resection of liver metastases before removal of the primary tumor (liver-first approach). With improvements in surgical technique and perioperative care over the past two decades, an increasing number of patients are being managed through a combined approach comprised of synchronous resection of the primary colorectal tumor and liver metastases. 7,8 Several studies have demonstrated the safety, efficacy, and feasibility of open synchronous resections (OSR), with acceptable morbidity, mortality, and long-term outcomes. 7,9,10 Furthermore, synchronous resection (SR) may offer several potential benefits for patients, including shorter overall hospital LOS, reduced costs, and the need to recover from only one major operation, while providing equivalent oncologic outcomes. 11,12 J Surg Oncol. 2019;119:30-39. wileyonlinelibrary.com/journal/jso 30 |

show abstract

One-stage, totally laparoscopic major hepatectomy and colectomy for colorectal neoplasm with synchronous liver metastasis: Safety, feasibility and short-term outcome

Cited by 43 publications

References 14 publications

Laparoscopic simultaneous resection of colorectal primary tumor and liver metastases: a propensity score matching analysis

Laparoscopic simultaneous resection of colorectal primary tumor and liver metastases: a propensity score matching analysis

Impact of totally laparoscopic combined management of colorectal cancer with synchronous hepatic metastases on severity of complications: a propensity-score-based analysis

Laparoscopic synchronous resection of colorectal cancer and liver metastases: A systematic review

Contact Info

Product

Resources

About