One‐session root canal treatment with antimicrobial photodynamic therapy (<scp>aPDT</scp>): an <i>in vivo</i> study

Borsatto, Maria Cristina; Correa-Afonso, Alessandra M.; Lucisano, Marília Pacifico; Silva, R A Bezerra da; Paula-Silva, Francisco Wanderley Garcia; Filho, Paulo Nelson; Silva, L A Bezerra da

doi:10.1111/iej.12486

Cited by 29 publications

(39 citation statements)

References 31 publications

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“…Desta mesma forma Borsatto et al realizaram um estudo em animais induzindo lesões periapicais, onde compararam a realização do tratamento endodôntico em uma sessão com a PDT, sem a aplicação da terapia e o tratamento em duas sessões com o uso de hidróxido de cálcio como medicação. Sendo que o uso de hidróxido de cálcio mostrou-se mais efetivo na diminuição da progressão da lesão (26). Já Ahangari et al em seu estudo mostraram a mesma eficácia antimicrobiana contra E. faecalis e C. albicans utilizando tanto a terapia fotodinâmica quanto o hidróxido de cálcio (24).…”

Section: Discussionunclassified

Terapia fotodinâmica na endodontia: revisão de literatura

Schaeffer¹,

D'Aviz²,

Ghiggi

et al. 2019

JOI

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A terapia endodôntica busca prevenir e quando necessário eliminar infecções endodônticas. A persistência de microrganismos ao preparo químico mecânico ou a medicação intracanal é considerada a principal causa dos insucessos do tratamento endodôntico. Sendo nestes casos o Enterococcus faecalis o microrganismo mais comumente encontrado. A terapia fotodinâmica (PDT) desponta desta maneira como uma promissora terapia coadjuvante ao tratamento endodôntico convencional para eliminar estes microrganismos persistentes. Esta terapia consiste na associação de uma fonte de luz específica a um fotossensibilizador na presença de oxigênio, produzindo assim espécies citotóxicas aos microrganismos. Assim, o presente artigo tem como objetivo realizar uma revisão de literatura sobre o uso da terapia fotodinâmica na endodontia, a qual demonstra-se efetiva como auxiliar durante o preparo do canal radicular.

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Section: Discussionunclassified

Terapia fotodinâmica na endodontia: revisão de literatura

Schaeffer¹,

D'Aviz²,

Ghiggi

et al. 2019

JOI

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“…These points motivate the use of an efficient alternative in the treatment of inflammatory processes around dental implants (7,8,16,17). aPDT has emerged in different dental environments as an alternative antimicrobial treatment demonstrating promising results (12,18,19). aPDT has a history in periodontics, but is still little discussed in implantology (7,8,16,20).…”

Section: Discussionmentioning

confidence: 99%

Is Antimicrobial Photodynamic Therapy Effective for Microbial Load Reduction in Peri‐implantitis Treatment? A Systematic Review and Meta‐Analysis

Fraga

Antunes

Fontes

et al. 2018

Photochem & Photobiology

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The systematic review and meta-analysis were undertaken to evaluate the effectiveness of antimicrobial photodynamic therapy (aPDT) in the microbiological alteration beneficial to peri-implantitis treatment. This study is registered with PROSPERO, number CRD42017064215. Bibliographic databases including Cochrane Library, Web of Science, Scopus and PubMed were searched from inception to 8 January 2017. The search strategy was assembled from the following MeSH Terms: "Photochemotherapy," "Dental Implants" and "Peri-Implantitis." Unspecific free-text words and related terms were also included. The Cochrane Collaboration's tool was used to evaluate the risk of bias of included studies. The random-effect model was chosen, and heterogeneity was evaluated using the I test. Three studies met the inclusion criteria. Meta-analysis demonstrated an association between aPDT and reduction in viable bacteria counts for: Aggregatibacter actinomycetemcomitans (OR = 1.31; confidence interval = 1.13, 1.49; P < 0.00001), Porphyromonas gingivalis (OR = 4.08; confidence interval = 3.22, 4.94; P < 0.00001) and Prevotella intermedia (OR = 1.66; confidence interval = 1.06, 2.26; P < 0.00001). A aPDT appears to be effective in bacterial load reduction in peri-implantitis and has a positive potential as an alternative therapy for peri-implantitis.

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“…18,12,19 aPDT is effective in killing oral microorganisms present in dentine caries that are produced in situ and in vitro and may be useful in minimally invasive dentistry. 20,21 Assuming that the in vitro and in situ techniques are effective, we suggest the following question: Is aPDT an effective coadjuvant therapy to reduce microorganisms in deep carious lesions?…”

Section: Discussionmentioning

confidence: 99%

Effect of the antimicrobial photodynamic therapy on microorganism reduction in deep caries lesions: a systematic review and meta-analysis

et al. 2016

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Abstract. This study aimed to perform a systematic review to assess the effectiveness of antimicrobial photodynamic therapy (aPDT) in the reduction of microorganisms in deep carious lesions. An electronic search was conducted in Pubmed, Web of Science, Scopus, Lilacs, and Cochrane Library, followed by a manual search. The MeSH terms, MeSH synonyms, related terms, and free terms were used in the search. As eligibility criteria, only clinical studies were included. Initially, 227 articles were identified in the electronic search, and 152 studies remained after analysis and exclusion of the duplicated studies; 6 remained after application of the eligibility criteria; and 3 additional studies were found in the manual search. After access to the full articles, three were excluded, leaving six for evaluation by the criteria of the Cochrane Collaboration's tool for assessing risk of bias. Of these, five had some risk of punctuated bias. All results from the selected studies showed a significant reduction of microorganisms in deep carious lesions for both primary and permanent teeth. The meta-analysis demonstrated a significant reduction in microorganism counts in all analyses (p < 0.00001). Based on these findings, there is scientific evidence emphasizing the effectiveness of aPDT in reducing microorganisms in deep carious lesions.

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One‐session root canal treatment with antimicrobial photodynamic therapy (aPDT): an in vivo study

Abstract: Two-session root canal treatment using a calcium hydroxide-based dressing was associated with significantly smaller periapical lesions at 90 days and characterized by progressive repair.

Cited by 29 publications

References 31 publications

Terapia fotodinâmica na endodontia: revisão de literatura

Terapia fotodinâmica na endodontia: revisão de literatura

Is Antimicrobial Photodynamic Therapy Effective for Microbial Load Reduction in Peri‐implantitis Treatment? A Systematic Review and Meta‐Analysis

Effect of the antimicrobial photodynamic therapy on microorganism reduction in deep caries lesions: a systematic review and meta-analysis

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