One Pot Synthetic Method of New Keto Diphenyl Selenide Compounds

Abstract

A series of hitherto unreported mono- and di-keto diphenyl selenides have been efficiently synthesized in high yields by treatment of diphenyl selenide (1) with appropriately substituted acyl chloride using anhydrous aluminum chloride as catalyst and methylene chloride as solvent. The structures of the synthesized compounds have been confirmed by elemental and spectral analysis.

Crystal structure and Hirshfeld surface analysis of (2E,2′E)-1,1′-[selenobis(4,1-phenylene)]bis[3-(4-chlorophenyl)prop-2-en-1-one]

“…The title compound was prepared according to a method proposed by Mechehoud et al (2010). 2-Chloro-1-(4-chlorophenyl)ethan-1-one (ClC 8 H 6 COCl; 36.5 mmol) and anhydrous aluminium chloride (5 g, 37.5 mmol, 3 equiv.)…”

Crystal structure of 1,1′-[selanediylbis(4,1-phenylene)]bis(2-chloroethan-1-one)

“…For details of how selenium functions as an antioxidant in conjunction with vitamin E, see: Ellis et al (1984). For the synthesis, see: Mechehoud et al (2010). For related structures, see: Zuo (2013); Bouraoui et al (2011) Table 1 Hydrogen-bond geometry (Å , ).…”

“…The title compound was prepared according to a method proposed by (Mechehoud et al, 2010). Methylene chloride acyl chloride, ClCH 2 COCl, (36.5 mmol) and anhydrous aluminium chloride 5 g (37.5 mmol, 3 eq) were taken in dry CH 2 Cl 2 (100 ml).…”